Daily non-political popular news in brief.
T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells
09-18-2007 · EurekAlert!Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia, according to researchers at Memorial Sloan-Kettering Cancer Center. By administering repeated doses of T cells designed to express an artificial receptor which recognizes human B cells, the researchers were able to eradicate cancer in 44 percent of mice bearing human ALL tumors.
Read more »
Keywords: re-engineered, human, cells, effectively, target, kill, cancerous, engineered, cell, cancerou
« Previous | Next »
Similar news on "T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells":
- Therapeutic peptide frees the protein p73 to kill tumor cells
03-08-2007 · EurekAlert!
p53 suppresses tumor development by inducing tumor cell death. However, targeting p53 for the treatment of cancer is confounded by the fact that genetic mutations cause loss or inactivation of p53 in approximately 50 percent of human cancers. Now, a new study indicates that targeting the p53-related protein p73 in mice induces the regression of established tumors of human origin, leading to the suggestion that p73 might be a viable target for developing anticancer therapeutics.
Similar news · Read more »
- Sidestepping cancer's chaperone
10-18-2007 · EurekAlert!
Researchers at the University of Massachusetts Medical School, have defined a method to target and kill cancer's 'chaperone' -- a protein that promotes tumor cell stability and survival -- without damaging healthy cells nearby.
Similar news · Read more »
- Jefferson scientists find tumor suppressor gene protects against pre-cancerous development
11-01-2006 · EurekAlert!
Cell biologists have provided further evidence that a gene thought to play a role in suppressing tumors actually protects against the development of pre-cancerous cell growth as well. The researchers say that the gene, caveolin-1, which they found in two major types of breast cells, could be a potential target for future drugs aimed at preventing breast cancer. The work also suggests a potentially important role of the tumor "microenvironment" in the cancerous process.
Similar news · Read more »
- Targeting tumors the natural way
03-25-2007 · EurekAlert!
By mimicking Nature's way of distinguishing one type of cell from another, University of Wisconsin-Madison scientists now report they can more effectively seek out and kill cancer cells while sparing healthy ones.
Similar news · Read more »
- Influenza: Insights into cell specificity of human vs. avian viruses
10-09-2007 · EurekAlert!
Researchers have identified which sites and cell types within the respiratory tract are targeted by human vs. avian influenza viruses, providing valuable insights into the pathogenesis of these divergent diseases. The report by van Riel et al, "Human and avian influenza viruses target different cells in the lower respiratory tract of humans and other mammals," appears in the October issue of the American Journal of Pathology, and is accompanied by a commentary and highlighted on the cover.
Similar news · Read more »
- A chemotherapy drug packs a one-two punch
02-20-2007 · EurekAlert!
How cancer cells are killed could turn out to be an important element in activating a patient's immune system. A new study shows that one chemotherapy drug may kill tumor cells in such a way that the immune system can recognize the cancerous cells and help fight the disease more effectively.
Similar news · Read more »
- Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
07-31-2007 · EurekAlert!
Working with human colorectal cancer cells, a University of Minnesota team, led by cancer biologists Zigang Dong and Ann Bode, has found the potential culprit among a network of enzymes that relay signals inside cells to regulate such functions as cell growth, cancer development and programmed cell death. The work suggests that drugs designed to disable the enzyme, known as TOPK, could have anticancer benefits. The study appears in the July issue of the journal Gastroenterology.
Similar news · Read more »
- Stanford researchers identify granddaddy of human blood cells
12-12-2007 · EurekAlert!
Researchers at the Stanford University School of Medicine have isolated a human blood cell that represents the great-grandparent of all the cells of the blood, a finding that could lead to new treatments for blood cancers and other blood diseases
Similar news · Read more »
- Overexcited neurons not good for cell health
12-17-2007 · EurekAlert!
A Northwestern University study reports that a mutation in a transcription factor that controls a neurotransmitter in the nematode C. elegans causes an imbalance in neuronal signaling that results in protein damage in target cells. Similar results and consequences on protein folding were found to occur upon exposure to the common toxins nicotine and lindane (a pesticide). Neurons become overexcited and fire incorrect signals too rapidly, resulting in proteins in target muscle cells becoming stressed, misfolding and becoming nonfunctional.
Similar news · Read more »
- A key antibody, IgG, links cells' capture and disposal of germs
11-13-2006 · EurekAlert!
Scientists have found a new task managed by the antibody that's the workhorse of the human immune system: Inside cells, Immunoglobulin G (IgG) helps bring together the phagosomes that corral invading pathogens and the potent lysosomes that eventually kill off the germs.
Similar news · Read more »
