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Brown scientists take the petri dish to new dimensions
09-19-2007 · EurekAlert!Brown University biomedical engineers have created a new method for growing cells in three dimensions rather than the traditional two. This 3-D petri dish allows cells to self-assemble, creating cell clusters that can be transplanted in the body or used to test drugs in the lab. This simple new technique is part of a growing body of research that shows that 3-D culture techniques can create cells that behave more like cells in the body.
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- Bacteria show promise in fending off global amphibian killer
05-23-2007 · EurekAlert!
First in a petri dish and now on live salamanders, probiotic bacteria seem to repel a deadly fungus being blamed for worldwide amphibian deaths and even extinctions. Though the research is in its early stages, scientists are encouraged by results that could lead the way to helping threatened species like mountain yellow-legged frogs of the Sierra Nevada mountains of southern California.
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- Cell growth technology promises more successful drug development
09-18-2007 · EurekAlert!
Scientists have developed unique technology to grow stem cells and other tissue in the laboratory in conditions similar to the way they grow in the human body. The technology, developed and patented by scientists at Durham University, UK, and its spin-out company ReInnervate Limited, is a plastic scaffold which allows cells to be grown in a more realistic three-dimensional form compared to the traditional flat surface of a Petri dish.
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- Scientists identify embryonic stem cells by appearance alone
08-27-2007 · EurekAlert!
Scientist can now identify pluripotent stem cells based solely on their physical appearance.
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- Scientists discover novel way to remove iron from ferritin
11-02-2007 · EurekAlert!
A new study led by Children's Hospital Oakland Research Institute senior scientist, Elizabeth Theil, PhD, is the first to suggest that a small protein or heptapeptide could be used to accelerate the removal of iron from ferritin. The results of this study may help scientists develop new medications that dramatically improve the removal of excess iron in patients diagnosed with blood diseases such as B-Thalassemia (Cooley's anemia) or sickle cell disease.
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- Brown scientists map structure of DNA-doctoring protein complex
12-06-2006 · EurekAlert!
Mobile DNA, which inserts foreign genes into target cells, is a powerful force in the march of evolution and the spread of disease. Working with the lambda virus and E. coli bacteria, Brown University biologists have solved the structure of a six-protein complex critical to performing this gene-grafting surgery. The technique they developed could be used to reveal the structure of other critical protein complexes, landing the work on the cover of Molecular Cell.
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- Morphine makes lasting -- and surprising -- change in the brain
04-25-2007 · EurekAlert!
Morphine stops the synapse-strengthening process in the brain known as long-term potentiation at inhibitory synapses, according to new research conducted by Brown University brain scientist Julie Kauer. In Nature, Kauer explains this startlingly persistent effect, which could contribute to addiction and may provide a target for treatments of opioid addiction. The research also supports a provocative theory of addiction as a disease of learning and memory.
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- The insides of clouds may be the key to climate change
02-17-2007 · EurekAlert!
As climate change scientists develop ever more sophisticated climate models to project an expected path of temperature change, it is becoming increasingly important to include the effects of aerosols on clouds, according to Joyce E. Penner, a leading atmospheric scientist at the University of Michigan.
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- How does soy promote weight loss? University of Illinois scientist finds another clue
05-01-2007 · EurekAlert!
Research shows that when soy consumption goes up, weight goes down. A new University of Illinois study may help scientists understand exactly how that weight loss happens.
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- Extraterrestrial impact likely source of sudden Ice Age extinctions
09-24-2007 · EurekAlert!
What killed the wooly mammoths? An international team of scientists, including Peter Schultz of Brown University, suggests that a comet or meteorite exploded over the planet roughly 12,900 years ago, causing the abrupt climate changes that led to the extinction of the wooly mammoth and other giant prehistoric beasts. Their theory is published in the Proceedings of the National Academy of Sciences.
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- Smaller is stronger -- now scientists know why
01-02-2008 · EurekAlert!
As metal structures get smaller -- as their dimensions approach the micrometer scale or less -- they get stronger. Now scientists from Lawrence Berkeley National Laboratory, Hysitron Inc. and General Motors Research and Development Center, working at the National Center for Electron Microscopy, have learned how. The researchers observed that compressing nanoscale pillars of nickel drives out dislocations and can produce a perfect crystal -- a process the researchers call "mechanical annealing."
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