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Giardia genome unlocked

Giardia lamblia, one of the most common human parasites in the United States, causes more than 20,000 intestinal infections a year, often through contact with contaminated drinking or swimming water. In the Sept. 28 issue of Science, an international team led by researchers at the MBL describe the complete genome (genetic sequence) of Giardia, which could lead to the development of new drugs to combat this persistent infection, called giardiasis.

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1. Scientists reveal structure of gateways to gene control
   03-28-2007 · EurekAlert!
   The first complete high-resolution map of structures that control how genes are packaged and regulated throughout an entire genome has been compiled by Penn State scientists. The research suggests how certain nucleosomes control whether a gene's function can be turned on. The study reveals an intimate relationship between the architecture of nucleosomes and the underlying DNA sequences they regulate, including a critical gateway that must be unlocked before a gene can be transcribed.
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2. Scientists sequence genome of intestinal parasite that afflicts hikers and kids in daycare
   09-27-2007 · EurekAlert!
   Giardia lamblia is a strange-looking parasite that swims in the gut, spreads through stool, persists in contaminated water, and is responsible for more than 20,000 reported infections a year in the US. An international team of researchers led by scientists at the Marine Biological Laboratory in Woods Hole, Mass., and funded by NIAID, one of the National Institutes of Health, describes the complete genetic sequence of the parasite.
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3. Gene Signatures Match Cancer And Other Diseases With Potentially Effective Drugs
   09-29-2006 · ScienceDaily
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4. Itsy bitsy genome
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10. Opossum genome sheds light on evolution
    05-09-2007 · Massachusetts Institute of Technology (MIT)
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