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UVA researchers explain cell response to skin-damaging UV rays
10-01-2007 · EurekAlert!Researchers at the University of Virginia Health System have published a new study that helps scientists around the world expand the body of knowledge on how cells protect themselves (or not) from DNA damage caused by UV rays. Their study reveals part of a 'simple switch' mechanism inside cells, triggered by UV exposure from the sun, that helps our cells survive and thrive after being exposed. This mechanism involves an unanticipated connection between several proteins in the cell, the researchers discovered.
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Keywords: uva, researchers, explain, cell, response, skin-damaging, rays, researcher, skin, damaging, ray
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- Iowa State astrophysicists provide the eyes for new gamma ray telescope system
04-19-2007 · EurekAlert!
Iowa State University researchers built the four cameras for the VERITAS telescope system in Arizona. The new $20 million telescope system detects gamma rays and will help astrophysicists explore distant regions of space, look for evidence of dark matter and help explain the origins of the most energetic radiation in the universe.
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- Researchers find suntan's 'master regulator'
03-08-2007 · EurekAlert!
A gene known to prevent cancer also acts as a master regulator of the suntan response, researchers report in the March 9, 2007 issue of Cell, published by Cell Press. The team discovered in studies of mice and human skin that p53, a gene best known for keeping tumors at bay, is ultimately responsible for activating the tanning machinery that darkens the skin of so many sun-seeking beachgoers, thereby protecting them from sunburns.
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- Scientists develop method to track immune system enzyme in live animals
05-17-2007 · EurekAlert!
Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development.
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- From managing sugar to managing healing
12-10-2006 · EurekAlert!
At the American Society for Cell Biology's 2006 conference, researchers will report that applying insulin directly to skin wounds significantly enhanced the healing process. Chronic or nonhealing wounds take an immense toll on American health and on health-care systems.
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- Gene analysis might explain ethnic differences in sensitivity to chemotherapy in lung cancer
04-23-2007 · UT Southwestern Medical Center
Analysis of three genetic mechanisms that cause non-small cell lung cancer might explain why East Asians respond better than other ethnic groups to a certain type of chemotherapy, a team led by UT Southwestern Medical Center researchers has found.
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- Loss of stem cells correlates with premature aging in animal study
06-06-2007 · EurekAlert!
Researchers at the Abramson Family Cancer Research Institute of the University of Pennsylvania have found that deleting a gene important in embryo development leads to premature aging and loss of stem cell reservoirs in adult mice. This gene, ATR, is essential for the body's response to damaged DNA, and mutations in proteins in the DNA damage response underlie certain types of cancer and other disorders in humans.
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- Genetic differences may help explain response to multiple sclerosis treatment
01-14-2008 · EurekAlert!
By comparing the DNA of patients with multiple sclerosis whose symptoms are reduced by interferon beta therapy to the DNA of those who continue to experience relapses, researchers may have identified important genetic differences between the two, according to an article posted online today that will appear in the March 2008 print issue of Archives of Neurology, one of the JAMA/Archives journals. These differences could eventually be used to help predict which treatments will help which patients.
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- Breast cancer susceptibility gene predicts outcome and response to treatment in lung cancer
09-25-2007 · EurekAlert!
Researchers have found that the breast cancer susceptibility gene, BRCA1, plays a significant role in nonsmall cell lung cancer. They told the European Cancer Conference in Barcelona that not only can it be used to predict outcome for patients with NSCLC, but it may also prove to be a valuable tool in choosing the best therapy for them.
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- Sidestepping cancer's chaperone
10-18-2007 · EurekAlert!
Researchers at the University of Massachusetts Medical School, have defined a method to target and kill cancer's 'chaperone' -- a protein that promotes tumor cell stability and survival -- without damaging healthy cells nearby.
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- Scientists overcome obstacles to stem cell heart repair
12-12-2007 · EurekAlert!
Scientists have overcome two significant obstacles on the road to harnessing stem cells to build patches for damaged hearts. Presenting the research at a UK Stem Cell Initiative conference the researchers will explain how they have made significant progress in maturing beating heart cells derived from embryonic stem cells and in developing the physical scaffolding that would be needed to hold the patch in place in the heart in any future clinical application.
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