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Drug has ability to cure type of leukemia

10-02-2007 · EurekAlert!

In people with chronic myeloid leukemia, the drug imatinib has been shown to drive cancer into remission, but the disease often returns when treatment is stopped. New research by UC Irvine scientists indicates that imatinib could cure CML under certain circumstances if it is taken over a long enough period of time.

Keywords: drug, ability, cure, type, leukemia

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Drug has ability to cure type of leukemia
10-02-2007 · EurekAlert!
In people with chronic myeloid leukemia, the drug Imatinib has been shown to drive cancer into remission, but the disease often returns when treatment is stopped. New research by UC-Irvine scientists indicates that Imatinib could cure CML under certain circumstances if it is taken over a long enough period of time.
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Kidney cancer drug attacks a major type of acute myeloid leukemia
01-29-2008 · EurekAlert!
A drug used to treat kidney cancer also targets a genetic mutation active in about one third of patients with acute myeloid leukemia, the most common and lethal form of adult leukemia, researchers at The University of Texas M. D. Anderson Cancer Center report in the Jan. 29 edition of the Journal of the National Cancer Institute.
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Their immune cells, fighting your cancer
09-19-2007 · EurekAlert!
Immune cells from "cancer-resistant" people could be used to help other people fight cancer. A scientist in the US has discovered that immune cells called granulocytes can kill cancer, and their effectiveness varies from person to person. The research team have now received permission from the US Food and Drug Administration to screen people for their ability to ward off cancer. Immune cells with the best cancer-fighting ability will be transferred to cancer patients, after being matched for blood type.
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'Modular' leukemia drug shows promise in early testing
06-28-2007 · EurekAlert!
A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia in both test tube and early animal tests, a new study shows. The agent represents a new class of agents called small modular immunopharmaceuticals. Called CD37-SMIP, the agent targets a protein called CD37 on the surface of these leukemia cells.
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Enhanced environment restores memory in mice with neurodegeneration
04-29-2007 · EurekAlert!
Mice whose brains had lost a large number of neurons due to neurodegeneration regained long-term memories and the ability to learn after their surroundings were enriched with toys and other sensory stimuli, new studies have shown. The scientists were able to achieve the same results when they treated the mice with a specific type of drug that encourages neuronal growth. The studies suggest two promising avenues for treatments for neurodegenerative diseases such as Alzheimer's disease.
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Leukemic cells find safe haven in bone marrow
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The cancer drug asparaginase fails to help cure some children with acute lymphoblastic leukemia (ALL) because molecules released by certain cells in the bone marrow counteract the effect of that drug, according to investigators at St. Jude Children's Research Hospital.
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Researchers learn why immune system's watch dogs howl
08-02-2007 · EurekAlert!
A class of proteins known as toll-like receptors are the guard dogs of the immune system, sniffing out bacteria or viruses then rousing the rest of the immune system for attack. Because of their ability to activate the body's defenses, toll-like receptors are a darling of drug developers. New research led by Brown University immunologist Wen-Ming Chu, M.D., identifies what protein alerts toll-like receptor 9, one of the most powerful guard dogs in the pack.
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Researchers develop simple method to create natural drug products
09-04-2007 · EurekAlert!
Until now, only the intricate machinery inside cells could take a mix of enzyme ingredients, blend them together and deliver a natural product with an elaborate chemical structure such as penicillin. Researchers at UC San Diego's Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences and the University of Arizona have for the first time demonstrated the ability to mimic this process outside of a cell.
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Protein's new role discovered in autoimmune disease
01-02-2008 · EurekAlert!
A chemical messenger has been shown to have a previously unknown major role in autoimmune diseases like arthritis and lupus. Investigators at the University of Alabama at Birmingham found interleukin 17 plays a major role on shaping B cells' ability to create more and more disease-causing antibodies, which may generate new ideas in the ongoing search for better drug targets.
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Cancer Drug May Be Remedy For Rheumatoid Arthritis, Study Finds
09-30-2006 · ScienceDaily
The potent cancer drug Gleevec, used to combat leukemia and some gastrointestinal cancers, may be useful in treating rheumatoid arthritis, according to a team of researchers at the Stanford University School of Medicine.
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