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Scripps research scientists develop innovative dual action anthrax vaccine-antitoxin combination
10-04-2007 · EurekAlert!Scientists at the Scripps Research Institute and the Salk Institute for Biological Studies have developed a new and highly effective agent that provides protection against anthrax by combining a fast-acting anthrax toxin inhibitor with a vaccine in a single compound.
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Keywords: scripps, research, scientists, develop, innovative, dual, action, anthrax, vaccine-antitoxin, combination, scripp, scientist, vaccine, antitoxin
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- Study identifies glucose 'sensor' that plays dual role in glucose metabolism and fat synthesis
12-26-2006 · EurekAlert!
In a new study, scientists at the Scripps Research Institute have described for the first time a glucose-activated sensor that acts as a switch to decrease production of endogenous glucose in the liver, and increase conversion of glucose to fat for storage in adipose tissue. This dual action makes the sensor, Liver X Receptor, a potential target for new therapies aimed at obesity and diabetes. The research may also have implications for heart disease and stroke.
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- Sheffield scientists light up bacteria
03-12-2007 · EurekAlert!
Researchers from the University of Sheffield have received joint funding from the Engineering and Physical Science Research Council (EPSRC) and the Ministry of Defense (MoD) to develop an innovative sensor to detect bacteria. The new method will use a polymer which will give a fluorescent signal when it encounters bacteria, allowing scientists to easily identify infected wounds much earlier than using conventional methodologies.
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- Reversing cancer cells to normal cells
04-29-2007 · EurekAlert!
A Northwestern University scientist describes new research that used an innovative experimental approach to provide unique insights into how scientists can change human metastatic melanoma cells back to normal-like skin cells -- by exposing the tumor cells to the embryonic microenvironment of human embryonic stem cells, the zebra fish and the chick embryo.
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- Scientists from Europe, Israel and the US develop robotic rats to aid in rescue missions
02-11-2008 · EurekAlert!
Based on principles of active sensing adopted widely in the animal kingdom, a multinational team of scientists is developing innovative touch technologies, including a "whiskered" robotic rat. The international consortium is investigating the ways in which rats use their bristly whiskers to explore their environment, and how the brain processes such information. The whiskered robot will hopefully aid in rescue missions, search missions under conditions of restricted visibility, as well as in planetary research
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- Scientists discover novel way to remove iron from ferritin
11-02-2007 · EurekAlert!
A new study led by Children's Hospital Oakland Research Institute senior scientist, Elizabeth Theil, PhD, is the first to suggest that a small protein or heptapeptide could be used to accelerate the removal of iron from ferritin. The results of this study may help scientists develop new medications that dramatically improve the removal of excess iron in patients diagnosed with blood diseases such as B-Thalassemia (Cooley's anemia) or sickle cell disease.
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- Progress in infectious disease surveillance but gaps remain, says Mailman School of Public Health
07-17-2007 · EurekAlert!
Although considerable progress has been made in global infectious disease surveillance, few scientists are optimistic that an effective early warning system is in place, and many gaps remain, according to researchers at Columbia’s Mailman School of Public Health. A paper in the July/August issue of Health Affairs, calls for increasing resources for improved coordination and sharing of information, and additional research to develop the most rigorous triggers for action.
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- Scripps research team blocks bacterial communication system to prevent deadly staph infections
10-30-2007 · EurekAlert!
In hopes of combating the growing scourge of antibiotic-resistant bacteria, in particular drug-resistant staph bacteria, a team of scientists from The Scripps Research Institute has designed a new type of vaccine that could one day be used in humans to block the onset of infection.
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- Scripps research study reveals structural dynamics of single prion molecules
02-12-2007 · EurekAlert!
Using a combination of novel technologies, scientists at the Scripps Research Institute and the Whitehead Institute for Biomedical Research have revealed for the first time a dynamic molecular portrait of individual unfolded yeast prions that form the compound amyloid, a fibrous protein aggregate associated with neurodegenerative diseases such as Alzheimer's disease and variant Creutzfeldt-Jacob disease -- the human version of mad cow disease.
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- Scripps scientists develop new tests that identify lethal prion strains quickly and accurately
12-04-2007 · EurekAlert!
Scientists at the Scripps Research Institute in Jupiter, Florida, have developed two new tests for prions, infectious proteins that cause a number of diseases including "mad cow disease," and a human counterpart, variant Creutzfeldt-Jakob disease. These advances open the door to better understanding and diagnosis of these troubling conditions.
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- Study offers innovative profile of enzyme that aids tumor growth
10-20-2006 · EurekAlert!
Using an innovative profiling strategy, scientists at the Scripps Research Institute have characterized an enzyme that is "highly elevated" in aggressive human tumor cells. When the enzyme, KIAA1363, was inactivated, it impaired tumor growth and migration in both ovarian and breast cancer cells, suggesting that inhibitors of this enzyme may prove valuable in the treatment of multiple types of cancer.
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