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Antibody leads to repair of myelin sheath in lab study of multiple sclerosis and related disorders
10-09-2007 · EurekAlert!Mayo Clinic researchers have found that a human antibody administered in a single low dose in laboratory mouse models can repair myelin, the insulating covering of nerves that when damaged can lead to multiple sclerosis and other disorders of the central nervous system.
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Keywords: antibody, leads, repair, myelin, sheath, lab, study, multiple, sclerosis, related, disorders, lead, sclerosi, disorder
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- USC study unravels key component in the process of myelination
11-02-2006 · EurekAlert!
A breakthrough finding on the mechanism of myelin formation by Jonah Chan, assistant professor of cell and neurobiology at the Keck School of Medicine of the University of Southern California, could have a major impact on the treatment of diseases such as multiple sclerosis and demyelination as a result of spinal cord injuries.
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- New imaging technique could promote early detection of multiple sclerosis
06-27-2007 · EurekAlert!
Researchers from Purdue University have studied and recorded how myelin degrades real-time in live mice using a new imaging technique. Myelin is the fatty sheath coating the axons, or nerve cells, that insulate and aid in efficient nerve fiber conduction. In diseases such as multiple sclerosis, the myelin sheath has been found to degrade.
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- Study reveals molecular basis of botulism toxin's deadly activity
12-14-2006 · EurekAlert!
Scientists at the Scripps Research Institute, the University of Wisconsin School of Medicine and Public Health, and the Howard Hughes Medical Institute have revealed in atomic detail how the toxins that cause botulism target and bind to nerve cells. This new understanding could ultimately lead to new ways for treating botulism, as well as to improved therapies for nervous system diseases such as dystonias, cerebral palsy and multiple sclerosis.
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- Animal study identifies potential treatment for Huntington's disease
10-08-2007 · EurekAlert!
Mass. General Institute for Neurodegererative Disorders researchers have identified a compound that may lead to a treatment that could protect against the effects of Huntington's Disease. Their report describes how a small molecule called C2-8 appears to delay the loss of motor control and reduce neurological damage in a mouse model of the disorder.
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- Ultra-high-field MRI allows for earlier diagnosis of multiple sclerosis
05-04-2007 · EurekAlert!
Ultra-high-field MRI can detect multiple sclerosis lesions better than MRI which can lead to possible earlier diagnosis and treatment, according to a new study by researchers from Ohio State University in Columbus, and Columbia University in New York.
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- New MRI finding sheds light on multiple sclerosis disease progressio
08-28-2007 · EurekAlert!
Using magnetic resonance images of the brain, researchers have identified a new abnormality related to disease progression and disability in patients with multiple sclerosis, according to a study published in the August issue of Radiology.
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- Both alcohol dependence and conduct disorder contribute to having a high number of sex partners
11-26-2007 · EurekAlert!
High-risk sexual behaviors can lead to unwanted pregnancies, infection and reproductive problems. A new study has linked the clinical diagnoses of alcohol dependence and conduct disorder in young adults to having 10 or more sexual partners. Although both disorders contribute to high-risk sexual behavior, alcohol dependence is the greater risk factor.
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- Loss of gene leads to protein splicing and buildup of toxic proteins in neurons
09-27-2007 · EurekAlert!
Researchers at Mayo Clinic in Jacksonville have discovered how loss of a gene can lead to accumulation of toxic proteins in the brain, resulting in a common dementia, and they say this mechanism may be important in a number of age-related neurological disorders.
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- Calcium is spark of life, kiss of death for nerve cells
02-28-2007 · EurekAlert!
Oregon Health & Science University research shows how calcium regulates the recharging of high-frequency auditory nerve cells after they've fired a signal burst. The study indicates calcium ions play a greater role in keeping in check the brain's most powerful circuits, such as those used for processing sound signals, than previously thought. A better understanding of that role could someday help prevent the death of neurons behind such neurological disorders as stroke and multiple sclerosis.
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- Moderate prenatal exposure to alcohol and stress in monkeys can cause touch sensitivity
02-07-2008 · EurekAlert!
A new study that exposed monkeys to moderate levels of alcohol and stress in pregnancy found increased sensitivity to touch in the monkeys' babies. Using a brain neuro-imaging technique, the researchers found that sensitivities to touch were related to changes in the brain chemical dopamine one area of the brain. Since sensitivity to touch in human children can lead to behavioral and emotional problems, this research has important implications for preventing childhood disorders.
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