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Ultra-low-dose aspirin might decrease bleeding severity in portal hypertension

A team led by Dr. Christian Doutremepuich from the University of Bordeaux 2 has determined that the paradoxical prothrombotic effects of ultra-low-dose aspirin, that could have beneficial properties decreasing bleeding complications of portal hypertension, are mediated by inhibition of Cyclooxygenase 2. This effect differs to the usual inhibition of Cyclooxygenase 1 at higher doses that has an antithrombotic action.

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Keywords: ultra-low-dose, aspirin, decrease, bleeding, severity, portal, hypertension, ultra, low, dose

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