Daily non-political popular news in brief.
Blocking cancer-causing gene improves radiation effectiveness, Jefferson researchers find
11-08-2006 · EurekAlert!Inhibiting a particular cancer-causing gene can enhance the cell-killing effects of radiation, a team of radiation oncologists and cancer biologists has found. Using a combination of zebrafish and antisense technology, they've shown that the drug flavopiridol works by blocking the activity of a gene, cyclin D1, which is overexpressed in about half of all breast cancers. Similar techniques in the future, the scientists say, may enable researchers to better gauge the effects of drugs.
Read more »
Keywords: blocking, cancer-causing, gene, improves, radiation, effectiveness, jefferson, researchers, cancer, causing, improve, researcher
« Previous | Next »
Similar news on "Blocking cancer-causing gene improves radiation effectiveness, Jefferson researchers find":
- Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer
10-11-2007 · EurekAlert!
A tumor-blocking protein previously implicated in prostate and breast cancer development may also be behind the most aggressive type of pancreatic cancer. Researchers have discovered that the protein pp32 -- which normally applies the brakes on a cancer-causing gene -- is missing in an aggressive form of pancreatic cancer. Though the work is preliminary, the scientists say, the absent protein could eventually become a marker for the disease and a potential drug target.
Similar news · Read more »
- Jefferson researchers boost immune 'killer cells,' increase antibody effectiveness against cancer
04-18-2007 · EurekAlert!
Researchers have devised a novel method to expand the number of immune system "natural killer (NK)" cells from blood cells outside the body. They have shown in laboratory studies that adding such cells to anti-cancer therapies involving monoclonal antibody drugs such as Herceptin, which targets the HER2/neu protein on breast cancer cells, is more effective in killing cancer cells, and perhaps someday may improve treatments.
Similar news · Read more »
- A friendly foe -- Bacteria residing in the gut boost immune response to tumors
07-26-2007 · EurekAlert!
Total body irradiation (TBI), which depletes the body of lymphocytes, improves the ability of tumor-specific T cells to cause tumor regression. In a new JCI study researchers show that, in mice, lymphodepletion does not fully account for the tumor regression observed following TBI. They show that disruption of the population of bacteria that normally reside in the gut without causing disease also plays a role in the effectiveness of this therapeutic approach against cancer.
Similar news · Read more »
- Jefferson scientists see breast cancer gene activity from outside the body
11-28-2007 · EurekAlert!
Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer Center in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body. This technology might someday help physicians to detect and classify cancer, enabling them to find cancerous breast tumors as early as possible, and determine the appropriate treatment.
Similar news · Read more »
- Keeping at-risk cells from developing cancer
12-10-2007 · EurekAlert!
Researchers at Johns Hopkins have discovered that cancers arising from epigenetic changes -- in this case the inappropriate activation of a normally silent gene -- develop by becoming addicted to certain growth factors. Reporting online in next week's Early Edition of the Proceedings of the National Academies of Sciences, the team shows that blocking this "addiction" can greatly prevent cancer growth.
Similar news · Read more »
- Cancer-resistant mouse discovered
11-27-2007 · EurekAlert!
A mouse resistant to cancer, even highly-aggressive types, has been created by researchers at the University of Kentucky. The breakthrough stems from a discovery by UK College of Medicine professor of radiation medicine Vivek Rangnekar and a team of researchers who found a tumor-suppressor gene called "Par-4" in the prostate.
Similar news · Read more »
- Jefferson researchers show chemotherapy and radiation together extend lung cancer patients' lives
11-09-2007 · EurekAlert!
Chemotherapy given at the same time as radiation therapy can help patients with a certain type of lung cancer live nearly 50 percent longer than they might have otherwise if the same treatment was given differently, according to an international team’s analysis of several trial results.
Similar news · Read more »
- Henry Ford Hospital expands research on gene and radiation therapy for prostate cancer
02-06-2008 · EurekAlert!
Henry Ford Hospital is embarking on an expanded major clinical trial involving the use of gene therapy in combination with radiation therapy, to determine if the combined treatment is more effective than radiation therapy alone for patients with intermediate risk prostate cancer.The clinical trial is part of a $9 million grant from the National Cancer Institute awarded to Henry Ford to study the effectiveness of gene therapy to treat prostate cancer.
Similar news · Read more »
- Turning a cellular sentinel into a cancer killer
01-24-2007 · EurekAlert!
Howard Hughes Medical Institute researchers have developed two strategies to reactivate the p53 gene in mice, causing blood, bone and liver tumors to self-destruct.
Similar news · Read more »
- Gene found to play a suppressor role in skin cancer development
02-06-2008 · EurekAlert!
Researchers at the Burnham Institute for Medical Research have provided genetic evidence that Activating Transcription Factor 2 plays a suppressor role in skin cancer development. ATF2 is a protein that regulates gene transcription, the first step in the translation of genetic code, in response to extracellular stresses such as ultraviolet light and ionizing radiation. This function of ATF2 in stress and DNA damage response suggests it may also play a role in tumor formation.
Similar news · Read more »
