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Growth factor signals influence balance between normal growth and cancerous growth
11-09-2006 · EurekAlert!Too much of a signaling protein called insulin-like growth factor-I (IGF-I) may fan the flames of cancer, while too little of the protein may cause short stature, dementia and osteoporosis. New research investigates how the growth hormone/IGF system is affected by the important tumor suppressor gene p53. This interplay of two signaling pathways reinforces questions about the long-term risks of prescribing growth hormone, while suggesting a future new avenue for cancer therapy.
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Keywords: growth, factor, signals, influence, balance, normal, cancerous, signal, cancerou
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