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Elevated nitric oxide in blood is key to high altitude function for Tibetans
10-30-2007 · EurekAlert!How can some people live at high altitudes and thrive while others struggle to obtain enough oxygen to function? The answer for Tibetans who live at altitudes around 14,000 feet is increased nitric oxide levels. High levels of NO circulate in various forms in the blood and produce the physiological mechanisms that cause the increased blood flow that maintains oxygen delivery despite hypoxia -- low levels of oxygen in the ambient air and the bloodstream.
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Keywords: elevated, nitric, oxide, blood, key, altitude, function, tibetans, tibetan
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For more information, please contact Ruth Metcalfe in the UCL Media Relations Office on tel: +44 (0)20 7679 9739, mobile: +44 (0)7990 675 947, out of hours: +44 (0)7917 271 364, e-mail: r.metcalfe@ucl.ac.uk2. 'Disruption of methylarginine metabolism impairs vascular homeostasis' is published in the February issue of the journal Nature Medicine. Advance online publication is embargoed to 18.00 GMT (13.00 US Eastern) Sunday 4 February 2007. Journalists can obtain copies of the paper by contacting the UCL Media Relations Office.3. The study was funded by the British Heart Foundation, the Wellcome Trust and the Medical Research Council. About UCL Founded in 1826, UCL was the first English university established after Oxford and Cambridge, the first to admit students regardless of race, class, religion or gender, and the first to provide systematic teaching of law, architecture and medicine. 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