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Normal tissue not spared in new forms of breast cancer radiotherapy
10-30-2007 · EurekAlert!A five-day course of radiotherapy to treat breast cancer may, in some cases, expose as much lung and heart tissue to potentially toxic radiation as does the standard six weeks of treatment, say researchers at Mayo Clinic Jacksonville.
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Keywords: normal, tissue, spared, forms, breast, cancer, radiotherapy, form
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- Newly created cancer stem cells could aid breast cancer research
08-13-2007 · EurekAlert!
Scientists have created breast cancer stem cells in culture by isolating and transforming a particular population of cells from normal human breast tissue. After being injected with just 100 of these transformed cells, mice develop tumors that metastasize. When scientists performed the same transformation process on a slightly different population of cells from the identical human breast tissue, the resulting cancer cells were 10,000 times less potent as tumor initiators and could not move to other tissues.
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- Surgical biopsy may reveal cancer in women with rare but benign breast condition
11-10-2006 · EurekAlert!
A study at Washington University School of Medicine in St. Louis showed that in women whose initial breast biopsies revealed certain rare, yet benign breast conditions, more extensive follow-up surgical biopsies found cancer up to 25 percent of the time. Most of the cancers were invasive, meaning the tumors had penetrated normal breast tissue and would require treatment.
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- Scientists take next step in understanding potential target for Ovarian cancer treatment
07-16-2007 · EurekAlert!
A traffic cop protein in the cell may have an even more important role: transporting a messenger protein that tells components in the nucleus to stop cell growth. Scientists are studying the normal function of a protein called 'km23', the traffic cop protein, because the team previously found altered forms of the protein in 42 percent of tumor tissue samples taken from women with Ovarian cancer. The discovery of this additional role may lead to diagnostic tools and earlier treatments for Ovarian cancer.
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- Mayo Clinic study observes normal aging process lowers breast cancer risk
11-14-2006 · EurekAlert!
Normal aging of breast tissue lessens breast cancer risk, reports a new study by Mayo Clinic Cancer Center researchers published in the Nov. 15 issue of the Journal of the National Cancer Institute.
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- Tumor-free breast tissue can have precancerous changes
01-10-2007 · EurekAlert!
A new study using mastectomy tissue shows that precancerous changes can occur in normal-appearing areas of the breast as distant as two inches from a tumor's edge. The findings, while preliminary, might have important implications for identifying breast-cancer patients at high risk of a second tumor in the same breast.
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- A new target for the treatment of breast cancer
01-11-2007 · EurekAlert!
The active ingredient in a drug currently being tested to treat rheumatoid arthritis might also one day serve as an effective means of treating one of the deadliest forms of breast cancer. Berkeley Lab researchers have demonstrated that inhibiting the activity of the protease enzyme known as TACE can deprive tumor cells of a key factor needed for their proliferation. TACE is strongly present in a form of breast cancer which responds poorly to current therapies.
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- Researchers identify unusual molecular switch for common form of advanced breast cancer
11-08-2007 · EurekAlert!
New evidence demonstrates that a novel molecular switch is involved in the development of a common form of advanced breast cancer, known as locally advanced breast cancer. The research, published by Cell Press in the Nov. 9, 2007 issue of Molecular Cell, provides an exciting paradigm shift in the understanding of a key event in breast cancer development and presents new therapeutic opportunities for this deadly disease.
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- World first test potential to identify breast cancer patients who will react badly to radiotherapy
04-19-2007 · EurekAlert!
Medical scientists at the University of Leicester have announced a potentially unique advance in breast cancer research by identifying two genes associated with adverse reaction to cancer treatment.
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- Almac Diagnostics announces pioneering genetic research on ductal carcinoma in situ
08-08-2007 · EurekAlert!
Today Almac Diagnostics announced a major study analyzing ductal carcinoma in situ tissue samples using its novel Breast Cancer DSA microarray. DSA research tools focus on the transcriptome of an individual disease, in this case breast cancer, and contain significant additional data relevant to the disease of interest that is not available on other generic microarrays.
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- Cells united against cancer
08-27-2007 · EurekAlert!
Sheets of highly organized epithelial cells line all the cavities and freesurfaces of the body, forming barriers that control the movement of liquidsand cells in the body organs. Now, the researchers at the University of Helsinki, Finland, have found that the organized structure of normal breast epithelial cells may also serve as a barrier against cancer.
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