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ADH2 and ALDH2 are associated with esophageal cancer

10-30-2007 · EurekAlert!

Esophageal cancer is a global health problem. A study led by Dr. Chun-Xia Yang recruited 191 esophageal cancer patients and 198 healthy controls from Yanting County. The research found that alcohol dehydrogenase 2 (ADH2) and aldehyde dehydrogenase 2 (ALDH2) genotypes are associated with esophageal cancer risk in Chinese. Furthermore, individuals with ADH2*1 allele and ALDH2*2 allele showed an elevated risk of developing esophageal cancer, especially among alcohol drinkers.

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Keywords: adh2, aldh2, associated, esophageal, cancer

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