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Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart
10-31-2007 · EurekAlert!According to a new study, recently published in Circulation Research, a journal of the American Heart Association, University of Missouri-Columbia researchers have demonstrated that a muscular dystrophy patient should be able to maintain a normal lifestyle if only 50 percent of the cells of the heart are healthy.
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Keywords: gene, stem, cell, therapy, needs, percent, effective, create, healthy, heart, need
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03-25-2007 · EurekAlert!
Previous research on the efficacy of stem cell therapy for heart repair has shown possible benefit from mesenchymal stem cells (MSCs) -- cells found in bone marrow that create connective tissue, bone and cartilage. A study presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit reveals the results of the first human trial using MSCs for the treatment of myocardial infarction (MI, or heart attack).
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- Penn researchers discover how microRNAs control protein synthesis
07-09-2007 · EurekAlert!
While most RNAs work to create, package and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression. Recently, researchers from the University of Pennsylvania School of Medicine determined how miRNAs team up with a regulatory protein to halt protein production.
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- Stem cells show promise for treating Huntington's disease
09-25-2007 · EurekAlert!
Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington's disease -- a fatal disorder for which there is currently no cure or even a treatment to slow the disease. Scientists used gene therapy to guide the development of endogenous stem cells in the brains of mice affected by a form of Huntington’s, generating new medium spiny neurons -- the cell lost in Huntington's disease.
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- Discovery of cardiac stem cells may advance regenerative heart therapy
11-22-2006 · EurekAlert!
An immediate early publication of the journal Cell, published by Cell Press, on Nov. 22, 2006, points to the possible existence of master cardiac stem cells with the capacity to produce all three major tissues of the mammalian heart. A companion Cell paper also published online reports the discovery of a second population of cardiac progenitors, which are capable of forming both cardiac muscle and the smooth muscle found in the heart's blood vessel walls.
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- UF researchers test stem cell therapy for heart patients
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- Enzyme delivered in smaller package protects cells from radiation damage
06-01-2007 · EurekAlert!
A University of Pittsburgh School of Medicine research team, collaborating with scientists from Stanford University, have developed a new, smaller gene therapy vector that may be effective in delivering a radioprotective enzyme systemically throughout the body which may spare healthy tissue the long-term consequences of therapeutic irradiation. These results also have implicatons for protecting first responders to a nuclear accident or terrorist attack.
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02-15-2007 · EurekAlert!
Cardiologists are increasingly using adult stem cells in clinical trials to repair hearts following heart attacks, but no one has understood how the therapy actually works. Now, in animal experiments, researchers at the University of Texas M. D. Anderson Cancer Center have deconstructed the process, describing how the stem cells fuse with heart muscle cells to create new cells that repopulate the ailing organ.
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The VCU Life Sciences Survey is the first poll to reflect the discovery reported internationally in November that human skin cells can be used to create stem cells or their near equivalents. When asked about the implications of this development, more than six in 10, or 63 percent, say that both embryonic and nonembryonic stem cell research is still needed, 22 percent say this development means embryonic stem cell research is no longer necessary.
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