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PET scan distinguishes Alzheimer's from other dementia
11-01-2007 · EurekAlert!A PET scan that measures uptake of sugar in the brain significantly improves the accuracy of diagnosing a type of dementia often mistaken for Alzheimer's disease, a study led by a University of Utah dementia expert has found.The scan, FDG-PET, helped six doctors from three national Alzheimer’s disease centers correctly diagnose frontotemporal dementia and Alzheimer's in almost 90 percent of cases.
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Keywords: pet, scan, distinguishes, alzheimer, dementia, distinguishe
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- Study confirms imaging compound identifies amyloid-beta in human brain
03-12-2007 · EurekAlert!
A team led by Massachusetts General Hospital investigators has confirmed that the imaging agent Pittsburgh Compound B (PiB) binds to the protein in amyloid plaques that characterize Alzheimer's disease in the human brain. Their report describes the first postmortem neuropathological study of a dementia patient who had previously participated in a PET imaging study using PiB.
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- Alzheimer's patient volunteers for first scan
11-24-2006 · EurekAlert!
The University of Manchester's Wolfson Molecular Imaging Centre will carry out its first positron emission tomography (PET) brain scan on a patient volunteer this Friday (24 November 2006) at 10:00.
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- Key Function Of Nervous System Enzyme Found; Impact On Drug Development Against Alzheimer's
09-29-2006 · ScienceDaily
Ever since scientists first elucidated the molecular mechanisms underlying the pathology and loss of nerve cells in Alzheimer's disease, drug companies have been working to develop drugs which will inhibit the outbreak of this severe form of dementia. Now researchers in Munich and Berlin (Germany) have discovered that an enyzme which has a central causal role in Alzheimer's disease happens also to have a key function in the normal development of the nervous system. This enzyme, beta-secretase or BACE1, ensures that nerve fibers (axons) are adequately isolated with sheaths of myelin, enabling rapid conduction of electrical impulses, as well as preventing short-circuits, akin to plastic insulation on electrical wires.
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- New imaging technique identifies people-at-risk for Alzheimer's disease
12-20-2006 · EurekAlert!
UCLA researchers used innovative brain scan technology with a new imaging molecule, invented at UCLA, to show that abnormal brain protein deposits that define Alzheimer's disease can be detected in people with mild cognitive impairment, a condition affecting 15-20 million Americans that increases risk for developing Alzheimer's disease. The new imaging technique helped researchers track disease progression over a two-year period and may be helpful in detecting pre-Alzheimer's conditions.
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- Estrogen use before 65 linked to reduced risk of Alzheimer's disease
05-02-2007 · EurekAlert!
Women who use hormone therapy before the age of 65 could cut their risk of developing Alzheimer's disease or dementia. This possibility is raised by research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28-May 5, 2007.
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- What's going on in the body? Advanced time-of-flight PET takes a superior 'look'
06-04-2007 · EurekAlert!
Moving from computer simulation to patient images, researchers are now demonstrating the benefits that time-of-flight/PET imaging can provide for cancer patients. The result? Superior images and shorter patient scan times for starters, according to a study released at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals, June 2-6 in Washington, D.C.
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- Decreased TGF-beta signaling might make you demented
11-01-2006 · EurekAlert!
The physical changes that occur in the brain of patients with Alzheimer's disease, the most common cause of dementia in the elderly, have been well-characterized, but the cause(s) of this disease and the development of therapies has remained elusive. A new study now shows that decreased signaling through a receptor known as T-beta-RII -- expression of which is decreased in the neurons of patients with AD -- increases neurodegeneration in mice.
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- Physicians enlisted in efforts to keep demented drivers off the road
12-21-2006 · EurekAlert!
The surge of baby boomers now entering their 60s means more drivers on the road who may be impaired by dementia or other cognitive impairments linked to aging. Researchers at the Alzheimer's Disease Research Center (ADRC) of Washington University School of Medicine in St. Louis and elsewhere have developed a three-hour workshop that trains health care providers to identify potentially unsafe drivers with dementia and to encourage appropriate retirement from driving.
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- Window into human behavior, brain disease seen in UCSF study
12-22-2006 · EurekAlert!
UCSF scientists have identified a cell population that is a primary target of the degenerative brain disease known as frontotemporal dementia, which is as common as Alzheimer's disease in patients who develop dementia before age 65.
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- How can we know early who will benefit from tumor target therapy?
11-21-2007 · EurekAlert!
A 55-year-old male patient had developed advanced hepatic metastasis and peritoneal carcinomatosis after remnant gastric cancer resection three months earlier. The patient only received target therapy, including Cetuximab plus recombinant human endostatin treatment. Anti-tumor activity assessed by 18F-fluorodeoxyglucose positron emission tomography/computer tomography scan at baseline, then every four weeks afterward showed that 18FDG-PET/CT could make an early prediction of the response to cetuximab plus Endostar in such clinical situations.
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