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Cold Spring Harbor Protocols highlights a method that captures cell growth and activity
11-01-2007 · EurekAlert!This month's issue of Cold Spring Harbor Protocols features a cutting-edge method that provides a snapshot of growth and activity patterns in mixed populations of cells. It also includes a related classic technique for the quantification of DNA and RNA in solutions.
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- A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
09-04-2007 · EurekAlert!
This month's release of Cold Spring Harbor Protocols includes free access to a protocol for generating mice with squamous cell carcinoma (SCC), one of the most common types of skin cancer. It also includes free access to an efficient method for testing individuals for specific DNA variations called SNPs (single-nucleotide polymorphisms), which will be useful for identifying individuals with disease-related mutations.
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- Cold Spring Harbor Protocols highlights reliable methods for gene and protein analyses
04-04-2007 · EurekAlert!
This month's release of Cold Spring Harbor Protocols highlights methods for creating and detecting specific proteins, as well as for characterizing the activities of specific genes during embryonic development. Two of the methods are freely available online.
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- Team of scientists develops non-invasive method to track nerve-cell development in live human brain
11-08-2007 · EurekAlert!
A team of scientists including researchers at Cold Spring Harbor Laboratory have identified and validated the first biomarker that permits neural stem and progenitor cells to be tracked, non-invasively, in the brains of living human subjects. This important advance could lead to significantly better diagnosis and monitoring of brain tumors and a range of serious neurological and psychiatric disorders.
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- RNA-based methods for developmental studies are featured in Cold Spring Harbor Protocols
02-01-2008 · EurekAlert!
This month's issue of Cold Spring Harbor Protocols highlights two methods to understand developmental processes in plants and flies. Both methods involve work with RNA and are freely accessible on the Web site for Cold Spring Harbor Protocols.
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- Bioinformatics-related methods are featured in Cold Spring Harbor Protocols
07-02-2007 · EurekAlert!
This month's release of Cold Spring Harbor Protocols highlights two articles that discuss the principles and applications of cutting-edge bioinformatics software programs.
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- Imaging techniques permit scientists to follow a day -- or four -- in the life of a cell
01-03-2007 · EurekAlert!
Understanding how live cells function is invaluable for molecular and cellular biologists, and advanced techniques to visualize cells in action are of great importance. The current issue of Cold Spring Harbor Protocols addresses this issue with two freely accessible protocols: one for inserting "reporter" proteins into cells to monitor what's going on inside, and another for maintaining the cells under a microscope for long-term observation.
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- Cost-effective method for gene silencing is featured in Cold Spring Harbor Protocols
08-01-2007 · EurekAlert!
The August, 2007 issue of Cold Spring Harbor Protocols includes a cost-effective approach for generating silencing RNAs, called esiRNAs, to efficiently target virtually any gene in mammalian cells.
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- Cold Spring Harbor Protocols features methods for visualizing protein dynamics
01-02-2008 · EurekAlert!
The January 2008 issue of Cold Spring Harbor Protocols highlights methods that permit scientists to observe protein dynamics in chromosomes and embryos.
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- Cold Spring Harbor Laboratory scientists discover new gene that prevents multiple types of cancer
02-09-2007 · EurekAlert!
A decades-old cancer mystery has been solved by researchers at Cold Spring Harbor Laboratory (CSHL). "We not only found a critical tumor suppressor gene, but have revealed a master switch for a tumor suppressive network that means more targeted and effective cancer therapy in the future," said CSHL Associate Professor Alea Mills, Ph.D. The study, headed by Mills, was published in the February issue of Cell.
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- Lighting up life: Cold Spring Harbor Protocols presents tips for creating glowing plants
02-01-2007 · EurekAlert!
The current issue of Cold Spring Harbor Protocols provides advice on choosing appropriate plant tissues, designing test proteins for maximal GFP detection and setting up microscope equipment for imaging in plants. This information will be useful to a broad range of scientists interested in plant biology and imaging technologies.
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