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Immune cell age plays role in retinal damage in age-related macular degeneration
11-01-2007 · EurekAlert!Studying a mouse model of age-related macular degeneration, the leading cause of blindness in older Americans, scientists at Washington University School of Medicine in St. Louis have found age is key in determining whether damaging blood vessels will form beneath the retina and contribute to vision loss.
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Keywords: immune, cell, age, plays, role, retinal, damage, age-related, macular, degeneration, play, related
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08-27-2007 · EurekAlert!
A team of scientists, including three researchers at George Mason University, found that the mineral zinc could play a role in the development of macular degeneration. In studying eye tissue samples, the researches found that deposits, that are hallmarks of age-related macular degeneration, contain large amounts of zinc. This finding, published in the journal Experimental Eye Research, might be particularly important because zinc supplements are widely given to patients to help boost weak immune systems.
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- Yerkes researchers pave the way for earlier diagnosis and treatment of retinal degenerative diseases
11-06-2006 · EurekAlert!
Researchers at the Yerkes National Primate Research Center, Emory University and the Atlanta VA Hospital have used magnetic resonance imaging to produce images of the eyeХs retinal layers. The research has the potential to revolutionize the way retinal degenerative diseases, such as retinitis pigmentosa, glaucoma, age-related macular degeneration and diabetic retinopathy, are diagnosed and treated. Accelerating detection and treatment of such diseases ultimately could help prevent vision loss.
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- Natural signal holds promise for psoriasis, age-related skin damage
06-28-2007 · EurekAlert!
The body may hold a secret to normalizing skin cell growth that is over zealous in psoriasis and non-melanoma skin cancers and too slow in aging and sun-damaged skin, researchers say.
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- Making daughters different -- How immune cells take divergent paths when fighting infections
03-01-2007 · EurekAlert!
How do immune cells decide to respond to invading microbes by either fighting to the death or becoming the body's memory for future infections? Researchers at the University of Pennsylvania School of Medicine have discovered that immune cells can differ in their inheritance of molecules that regulate cell fate, and therefore what role they play in fighting infection.
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- New gene linked to macular degeneration risk
10-19-2006 · EurekAlert!
Researchers at the John A. Moran Eye Center at the University of Utah have identified a gene called HTRA1 that contributes to a major risk of age related macular degeneration, the most common cause of irreversible vision loss in the developed world. The discovery of this gene allows anyone to take a simple blood test to find out if they are up to 700 percent more likely to develop AMD than the average person.
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- Lessons in wood formation from Arabidopsis
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05-17-2007 · EurekAlert!
Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development.
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- Area deep within the brain found to play role in sensory perception
09-24-2007 · EurekAlert!
A new study to be published in Annals of Neurology, the official journal of the American Neurological Association, found that the VL also plays a role in sensory processing and that damage to this area leads to functional and neural changes.
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02-06-2008 · EurekAlert!
Researchers at the Burnham Institute for Medical Research have provided genetic evidence that Activating Transcription Factor 2 plays a suppressor role in skin cancer development. ATF2 is a protein that regulates gene transcription, the first step in the translation of genetic code, in response to extracellular stresses such as ultraviolet light and ionizing radiation. This function of ATF2 in stress and DNA damage response suggests it may also play a role in tumor formation.
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- Scientists discover zinc link to a leading cause of blindness
03-22-2007 · EurekAlert!
Scientists at the University of Texas Medical Branch at Galveston and Neurobiotex, Inc. have found high levels of zinc in amyloid plaque deposits in the eye that are an indication of age-related macular degeneration (AMD). The discovery marks an additional similarity between AMD plaques and those seen in Alzheimer's disease and could facilitate the development of effective treatments for AMD.
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