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The chemical peroxynitrite tolerates pain

11-01-2007 · EurekAlert!

The repeated use of opiates such as morphine to relieve chronic pain results in individuals having to take higher and higher doses to achieve equivalent pain relief. A new study has identified a role for the chemical peroxynitrite in this process in mice, leading to the suggestion that targeting ONOO' might provide an adjunct therapy for individuals using opiates to relieve chronic pain.

Keywords: chemical, peroxynitrite, tolerates, pain, tolerate

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JCI table of contents: Nov. 1, 2007
11-01-2007 · EurekAlert!
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published Nov. 1, 2007, in the JCI, including: Mice predict the effectiveness of orally taken drugs; Stressed out skin loses its antimicrobial defense mechanism; The chemical peroxynitrite tolerates pain; OX40L helps trigger anti-cancer immune responses; Macrophages are not all seeing in the eye; I(r)oning out the mechanism of kidney functions; and others.
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Watching funny shows helps children tolerate pain longer, study finds
10-23-2007 · EurekAlert!
Watching comedy shows helps children tolerate pain for longer periods of time, according to a study by UCLA's Jonsson Comprehensive Cancer Center and the nonprofit organization Rx Laughter.
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New brain-chemistry differences found in depressed women
11-06-2006 · EurekAlert!
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Pleasure and pain: Study shows brain's 'pleasure chemical' is involved in response to pain too
10-18-2006 · EurekAlert!
For years, the brain chemical dopamine has been thought of as the brain's "pleasure chemical," and studies have linked the addictive properties of drugs like cocaine to their effects on the dopamine system. But now, a new study adds a new twist to dopamine's fun-loving reputation: pain.
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Radiotracers For Imaging Studies In Addiction: How Chemistry Enhances Ability To See Inside The ...
09-29-2006 · ScienceDaily
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10-17-2006 · EurekAlert!
Scientists have observed a first: direct electricity-shuttling from a protein to a mineral. Reporting in the current advance online edition of the Journal of the American Chemical Society, they suggest that proteins -- removed from the outer membrane of a versatile, metal-altering soil bacterium -- could make miniature bioreactor cells feasible. Biologically speaking, the feat is the bacterial equivalent of removing lungs and coaxing the disembodied tissue to breathe.
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ACS News Service Weekly PressPac -- Nov. 1, 2006
11-06-2006 · EurekAlert!
The American Chemical Society News Service Weekly Press Package with reports from 35 major peer-reviewed journals on chemistry, health, medicine, energy, environment, food, nanotechnology and other hot topics.
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11-16-2006 · EurekAlert!
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Special ES&T issue examines effects of emerging contaminants on people, planet
11-30-2006 · EurekAlert!
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Taking nanolithography beyond semiconductors
12-14-2006 · EurekAlert!
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