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Stimulant Inaction: ADHD drug's mental lift proves surprisingly weak

A widely used drug often calms children with attention-deficit hyperactivity disorder but does little to alleviate the condition's underlying mental deficits.

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Keywords: stimulant, inaction, adhd, drug, mental, lift, proves, surprisingly, weak, prove

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1. Med-Start Kids: Pros, cons of Ritalin for preschool ADHD
   10-28-2006 · Science News Online
   A long-term study indicates that 3- to 5-year-olds with attention-deficit hyperactivity disorder who are prescribed the stimulant Ritalin often show behavioral improvements but also display greater sensitivity to the drug's side effects than older children do.
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2. Mayo Clinic study indicates medication for ADHD may help student outcomes
   09-18-2007 · EurekAlert!
   In an 18-year-study on attention-deficit/hyperactivity disorder, Mayo Clinic researchers found that treatment with prescription stimulants is associated with improved long-term academic success of children with ADHD. The Mayo Clinic results are the first population-based data to show stimulant drug therapy helps improve long-term school outcomes.
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3. Shire analysis compares stimulant to nonstimulant ADHD medications in patients aged 8 to 15 years
   11-16-2006 · EurekAlert!
   Shire plc announced study results that suggested that stimulant medications such as Adderall XR (mixed salts of a single-entity amphetamine product) are significantly more effective than nonstimulant medications in the treatment of patients aged 8 to 15 years with Attention-Deficit/Hyperactivity Disorder. The study, a meta-analysis of 29 studies undertaken during the last 25 years with nearly 4,500 children with ADHD, was presented at the U.S. Psychiatric and Mental Health Congress.
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4. Shire bioequivalence study results of SPD465, investigational drug for adults with ADHD
   11-16-2006 · EurekAlert!
   Shire plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announced that a single once-daily morning dose of the investigational amphetamine compound SPD465, extended release triple-bead mixed amphetamine salts, designed to reduce symptoms of Attention-Deficit/Hyperactivity Disorder in adults for up to 16 hours, was bioequivalent to a dose of ADDERALL XR (mixed salts of a single-entity amphetamine product) followed by a dose of mixed amphetamine salts immediate release ("MAS IR") eight hours later, at the US Psychiatric & Mental Health Congress.
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5. Does Stimulant Treatment for ADHD Increase Risk of Drug Abuse?
   06-18-2007 · Brookhaven National Laboratory
   Parents, doctors, and others have wondered whether common treatments for attention-deficit hyperactivity disorder (ADHD) inadvertently predispose adolescents to future drug abuse. The answer may depend on the age at which treatment is started and how long it lasts, say the authors of a new brain-imaging and behavioral study conducted in animals at Brookhaven National Laboratory.
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6. Drug-free treatments offer hope for older people in pain
   09-10-2007 · EurekAlert!
   Mind-body therapies, which focus on the interactions between the mind, body and behavior, and the ways in which emotional, mental, social and behavioral factors can affect health, may be of particular benefit to elderly chronic pain sufferers. A new study published in Pain Medicine provides a structured review of eight mind-body interventions for older people, including progressive muscle relaxation, meditation, hypnosis, tai chi and yoga.
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7. Medicine proves a promising treatment in the battle against alcohol dependence
   10-09-2007 · EurekAlert!
   Researchers at the University of Virginia have led a multisite clinical trial showing that the drug topiramate is significantly more efficacious than placebo at curbing alcohol dependence. Subjects had to be drinking heavily and were not abstinent when they started the trial.
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8. Researchers call for investigation into links between khat use and psychiatric disorders
   06-04-2007 · EurekAlert!
   Researchers investigating the evidence for a potential causal link between khat use and mental illness have called for improved research on the stimulant plant, and its possible association with psychiatric disorders. The researchers suggest that only by improving the quality of future research, and integrating social, medical and pharmacological studies, can a more incisive understanding of the psychological and social impact of khat on individuals and communities be gained.
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9. ADHD Appears to Be Associated With Depressed Dopamine Activity in the Brain
   08-06-2007 · Brookhaven National Laboratory
   Adults with attention-deficit/hyperactivity disorder (ADHD) show a blunted response to the drug methylphenidate (Ritalin), which increases brain dopamine levels. This suggests that dopamine dysfunction may be involved with ADHD symptoms and may contribute to substance abuse that often occurs simultaneously.
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10. Researchers discover possible markers for mental illness
    12-03-2007 · EurekAlert!
    Researchers have discovered natural genetic differences that might help predict the most effective antipsychotic drugs for particular patients with mental disorders such as schizophrenia, Parkinson's and drug addiction. They found the differences in the gene for a molecule called the dopamine D2 receptor, a protein present on brain cells that are sensitive to the neurotransmitter dopamine.
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