Daily non-political popular news in brief.
Study identifies novel gene alterations in lung cancer
11-04-2007 · EurekAlert!Unprecedented study of the genomic landscape of lung cancer identifies key gene alteration not previously implicated in any form of cancer.
Read more »
Keywords: study, identifies, novel, gene, alterations, lung, cancer, identify, alteration
« Previous | Next »
Similar news on "Study identifies novel gene alterations in lung cancer":
- Study identifying alteration in gene associated with uterine cancer
05-22-2007 · EurekAlert!
Researchers at the Translational Genomics Research Institute today announced the discovery of previously unrecognized alterations in a gene called FGFR2 in a subset of endometrial cancers, the most common gynecologic cancer in the United States. The mutations in FGFR2 result in uncontrolled cell division, a hallmark of cancer.
Similar news · Read more »
- Novel EGFR ectodomain mutations in glioblastoma
12-18-2006 · EurekAlert!
The Epidermal Growth Factor Receptor, a so-called kinase protein, is often abnormally active in cancer. A new class of anticancer drugs inhibiting the activated EGFR kinase have shown to be effective against such cancers, especially lung cancer. In a new study in PLoS Medicine, researchers have catalogued and characterized the mutations in the EGFR gene that occur in glioblastoma, a deadly type of brain tumor.
Similar news · Read more »
- Pioneering study looks at p53’s Role in tumor-stroma interactions
10-25-2006 · EurekAlert!
Researchers have conducted the first comprehensive study of the role an important tumor suppressor gene plays in cancer development. P53 is known as a major tumor suppressor that is frequently mutated in human cancer. In this study, researchers used novel proteomic techniques to identify the proteins secreted by cells specifically in response to p53. The findings suggest a newfound role for wt-p53 in the control of the tumor's ability to communicate with the normal stromal cells surrounding it.
Similar news · Read more »
- Pioneering study looks at p53's role in tumor-stroma interactions
10-25-2006 · EurekAlert!
Researchers have conducted the first comprehensive study of the role an important tumor suppressor gene plays in cancer development. P53 is known as a major tumor suppressor that is frequently mutated in human cancer. In this study, researchers used novel proteomic techniques to identify the proteins secreted by cells specifically in response to p53. The findings suggest a newfound role for wt-p53 in the control of the tumor's ability to communicate with the normal stromal cells surrounding it.
Similar news · Read more »
- Multicenter study nets new lung tumor-suppressor gene
08-05-2007 · EurekAlert!
Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice. The researchers report in the journal Nature that LKB1 is not only a "tumor-suppressor" gene for nonsmall cell lung cancer in mice, it also may be more powerful than other, better-known suppressors. The study will be published on the journal's Web site on Aug. 5.
Similar news · Read more »
- Researchers identify how to switch off cancer cell genes
11-12-2007 · EurekAlert!
A new study led by researchers at the University of Southern California identifies how genes are silenced in cancer cells through distinct changes in the density of nucleosomes within the cells.
Similar news · Read more »
- Scientists identify a gene that may suppress colorectal cancer
03-21-2007 · EurekAlert!
In Genome Research, a husband-and-wife research team from Thomas Jefferson University report the discovery of a gene that, when mutated, may suppress colorectal cancer. To conduct the study, the researchers used a strain of mice that develop polyps, or small growths of tissue, in the digestive tract -- the harbingers of cancer. When these mice possessed one copy of the mutated gene, the incidence of small intestinal and colon polyps were reduced by about 90 percent.
Similar news · Read more »
- Other highlights in the Aug. 7 JNCI
08-07-2007 · EurekAlert!
Also in the Aug. 7 JNCI are a study showing vitamins and minerals do not improve liver cancer survival, another study on testicular cancer survivors' survival rates for second cancers, a gene expression pattern that predicts lung cancer prognosis and epigenetic changes in Wilms tumor.
Similar news · Read more »
- Genetic approach provides new insight into trastuzumab resistance in breast cancer
10-15-2007 · EurekAlert!
A new study provides important insight into the mechanisms involved in resistance to treatment of breast cancer patients with trastuzumab (Herceptin). The research, published by Cell Press in the October issue of the journal Cancer Cell, identifies markers that may help to identify patients who are unlikely to respond to trastuzumab treatment and provides a potential strategy for treating these patients.
Similar news · Read more »
- Novel EGFR antibody outperforms cetuximab in mouse model of lung cancer
01-26-2007 · EurekAlert!
A study conducted at the Dana-Farber Cancer Institute and the Ludwig Center at Dana-Farber/Harvard Medical School now suggests that antibodies binding a particular protein conformation, caused by hyperactivation, might have distinct therapeutic advantages over antibodies, like cetuximab, that bind to wild-type (normal) target proteins.
Similar news · Read more »
