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Genome study charts genetic landscape of lung cancer

11-04-2007 · EurekAlert!

An international team of scientists today announced the results of a systematic effort to map the genetic changes underlying lung cancer, the world's leading cause of cancer deaths.

Keywords: genome, study, charts, genetic, landscape, lung, cancer, chart

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Study charts genomic landscape of lung cancer
11-07-2007 · Massachusetts Institute of Technology (MIT)
An international team of scientists has produced the most comprehensive view yet of the abnormal genetic landscape of lung cancer. The research reveals more than 50 genomic regions that are frequently gained or lost in human lung tumors.
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Gene variations point to why lung cancer drugs work better in Japanese vs. US patients
06-02-2007 · EurekAlert!
Recent clinical trials revealed that Japanese lung cancer patients survived longer and had a higher rate of side effects than US patients taking the same two drugs, paclitaxel and carboplatin. Now a new study by the Southwest Oncology Group uncovers genetic differences that may explain why. The results, embargoed for release 8:30 a.m. ET Saturday, June 2, are being highlighted at the American Society of Clinical Oncology annual meeting.
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Genes key to high liver cancer rates in men
01-15-2008 · Massachusetts Institute of Technology (MIT)
A fundamental difference in the way males and females respond to chronic liver disease at the genetic level helps explain why men are more prone to liver cancer, according to MIT researchers, who conducted the first genome-wide study on the subject.
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Study identifies novel gene alterations in lung cancer
11-04-2007 · EurekAlert!
Unprecedented study of the genomic landscape of lung cancer identifies key gene alteration not previously implicated in any form of cancer.
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Researchers chart the genetic mechanisms behind the genesis of fat cells
11-06-2007 · EurekAlert!
Obesity is a well known risk factor for prostate, breast and colon cancer, but recent studies have shown that a protein responsible for generating fat cells also plays an important role in cancer. Researchers at the Genome Institute of Singapore have conducted, for the first time, a genome-wide analysis of how the protein, called perixosome proliferator-activated receptor gamma, turns on various genes related to obesity.
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Study finds gene linked to aggressive prostate cancer
12-11-2007 · EurekAlert!
Results from two genome-wide association studies have identified a genetic variant of the DAB2IP gene that is associated with the risk of aggressive prostate cancer. Research teams from the Translational Genomics Research Institute, Wake Forest University School of Medicine, the Karolinska Institute in Stockholm, Sweden, and Johns Hopkins Medical Institutions made the discovery jointly.
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Tumor genome analysis unveils new insights into lung cancer
11-04-2007 · EurekAlert!
An international consortium of scientists today in an advanced online publication in the journal Nature revealed a comprehensive view of the altered genetic background of the type of lung cancer that is the most common cause of cancer deaths in humans.
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Genetic map offers new tool for malaria research
12-10-2006 · EurekAlert!
An international research team has created a genome-wide map that charts the genetic variability of the human malaria parasite Plasmodium falciparum. The study reveals striking variation within the pathogen's genome, and lays the foundation for dissecting the functions of important parasite genes and for tracing the global spread of malaria. Already, the tool has helped to unearth novel genes that may underlie resistance to current drugs against malaria.
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Researchers provide genetic associations from a genome-wide scan for cardiovascular disease traits
09-19-2007 · EurekAlert!
Researchers from Boston University School of Medicine, Boston University School of Public Health and the National Heart, Lung and Blood Institute, have completed analyses of a genome-wide scan on a group of two generations of participants from the landmark Framingham Heart Study.
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Researchers publish largest genome-wide study of prostate cancer in African American men
10-11-2006 · EurekAlert!
Researchers from 14 institutions across the country today announced the results of the first genome-wide linkage study of prostate cancer in African Americans. Using genetic markers, researchers identified several regions of the human genome that likely contain genes that, when altered, increase the risk of developing prostate cancer.
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