Daily non-political popular news in brief.
UCSD researchers discover inflammation, not obesity, cause of insulin resistance
11-06-2007 · EurekAlert!Researchers at the University of California, San Diego School of Medicine have discovered that inflammation provoked by immune cells called macrophages leads to insulin resistance and type 2 diabetes. Their discovery may pave the way to novel drug development to fight the epidemic of type 2 diabetes associated with obesity, the most prevalent metabolic disease worldwide.
Read more »
Keywords: ucsd, researchers, discover, inflammation, obesity, cause, insulin, resistance, researcher
« Previous | Next »
Similar news on "UCSD researchers discover inflammation, not obesity, cause of insulin resistance":
- A unique twin study on the increased cardiometabolic risk in obesity
02-13-2007 · EurekAlert!
A unique monozygotic twin study by Finnish researchers found that obesity, already in its early stages and independent of genetic influences, is associated with deleterious alterations in the lipid metabolism known to facilitate atherogenesis, inflammation and insulin resistance. By studying monozygotic twins discordant for obesity the research group was able to eliminate effects caused by genetic differences related to obesity and reveal effects attributable to environmental and life-style differences.
Similar news · Read more »
- JCI table of contents: October 19, 2006
10-19-2006 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, October 19, 2006, in the JCI, including: Double trouble for RA patients: PLC-gamma-2 regulates osteoclastogenesis and B cell differentiation; Role for NF-kappa-B in endothelial cell function; CYLD puts a damper on inflammation; Triggering TLR4 can raise resistance to insulin; TLR4 performs a balancing act in the lungs; and Hyperactive osteoclasts cause osteoporosis in neurofibromatosis type 1 patients.
Similar news · Read more »
- UCSD researchers discover internal compass of immune cell
12-14-2006 · EurekAlert!
Researchers at the UCSD School of Medicine have discovered how neutrophils -- specialized white blood cells that play key roles in inflammation and in the body's immune defense against bacteria -- navigate to sites of infection and inflammation. These findings could potentially lead to new treatments for serious infections and inflammatory diseases in patients.
Similar news · Read more »
- UCSD researchers discover cause of rosacea
08-05-2007 · EurekAlert!
A team of researchers, led by Richard L. Gallo, M.D., Ph.D., professor of medicine and chief of the Division of Dermatology at the University of California, San Diego School of Medicine and the dermatology section of the Veterans Affairs San Diego Healthcare System, has determined that it is not one, but a combination of two abnormal factors, that result in rosacea.
Similar news · Read more »
- Story ideas from the Journal of Lipid Research
01-10-2008 · EurekAlert!
Metabolic syndrome, a collection of related abnormalities like hypertension, obesity, insulin resistance, and excess cholesterol, poses a major risk for developing heart disease and diabetes. Individuals with a genetic predisposition to high cholesterol can be especially vulnerable to metabolic syndrome, but researchers have now found that blocking the enzyme stearoyl-CoA desaturase-1, which helps synthesize unsaturated fatty acids, greatly improves the profile of FH-mice affected by metabolic syndrome.
Similar news · Read more »
- Stress-signaling fat is a culprit behind insulin resistance
03-06-2007 · EurekAlert!
A new study in the March issue of the journal Cell Metabolism, published by Cell Press, has identified a common link between multiple assaults on the body, including saturated fats, obesity, and certain types of drugs, all of which can lead to insulin resistance. The researchers found that these metabolic stresses lead to an upswing in production of a particular kind of fat molecule, known as ceramide.
Similar news · Read more »
- NIH researchers discover protein that appears to regulate bone mass loss, the cause of osteoporosis
03-05-2007 · EurekAlert!
An estimated ten million Americans suffer from osteoporosis, and another 34 million Americans are at risk of developing the disease. The basic mechanism behind osteoporosis involves an imbalance between bone mineral formation and loss, but the detailed biological processes that lead to this imbalance are not completely understood. Now researchers at NIAID and colleagues are reporting new insights into the biology of bone loss based on a study of 14 people with a rare genetic disorder called X-linked Hyper IgM Syndrome.
Similar news · Read more »
- Mayo Clinic shows therapy effective for reducing lupus flares
11-09-2007 · EurekAlert!
Mayo Clinic researchers have shown that an immunosuppressive drug used in organ transplant cases is effective in reducing flare-ups in patients with systemic lupus erythematosus. SLE results in inflammation of connective tissues and can involve the skin, joints and kidneys. Its cause is unknown. The findings were announced today at the annual meeting of the American College of Rheumatology in Boston.
Similar news · Read more »
- Researchers discover genetic cause for word-finding disease
01-15-2007 · EurekAlert!
Northwestern University researchers have discovered a genetic cause of a mysterious neurological disease in which people have trouble recalling and using words. The illness, Primary Progressive Aphasia, differs from Alzheimer's Disease in which a person's memory becomes impaired. In PPA, which can begin in the 40's and 50's, people eventually lose the ability to express themselves and understand speech. Although people lose the ability to communicate, they are still able to perform complicated tasks.
Similar news · Read more »
- Bleeding, not inflammation, is major cause of early lung infection death
08-27-2007 · EurekAlert!
Researchers believe they have discovered why a bacterial lung infection is so lethal in the early stages, and it's not what medical authorities had thought, according to research published August 23 in the journal Immunity.
Similar news · Read more »
