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Blood pressure drug curbs brain damage from PTSD

11-06-2007 · EurekAlert!

A drug used to treat high blood pressure and enlargement of the prostate may protect the brain from damage caused by post-traumatic stress disorder, Alzheimer's disease, depression and schizophrenia. Prazosin, also prescribed as an antipsychotic medication, appears to block the increase of steroid hormones known as glucocorticoids, Portland researchers have found. Elevated levels of glucocorticoids are associated with atrophy in nerve branches where impulses are transmitted, and even nerve cell death, in the hippocampus.

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Keywords: blood, pressure, drug, curbs, brain, damage, ptsd, curb

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