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Progress toward new therapies for coronary artery disease

Coronary artery disease is a leading cause of mortality in Western countries. It cannot be cured. Recent research, led by Pilar Ruiz-Lozano, PhD, at the Burnham Institute for Medical Research, may lead to new therapies for coronary artery disease.

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Keywords: progress, toward, therapies, coronary, artery, disease, therapy

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1. Pairing medical therapy with coronary intervention fails to reduce heart disease deaths
   03-26-2007 · EurekAlert!
   Results of research presented today at the American College of Cardiology’s 56th Annual Scientific Session showed that percutaneous coronary interventions combined with optimal medical therapy (OMT) was no more effective than OMT alone in preventing heart attacks and other cardiac events among patients with coronary artery disease. The study will be simultaneously published in the New England Journal of Medicine and will appear in the April 12 print issue.
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2. Study finds coronary procedure adds no benefit over 'optimal medical therapy' alone
   03-27-2007 · EurekAlert!
   Percutaneous coronary intervention plus optimal medical therapy does not improve outcomes in patients with coronary artery disease, compared with optimal medical therapy alone, according to study results presented yesterday at the 56th Annual Scientific Session of the American College of Cardiology in New Orleans, and published online in the New England Journal of Medicine.
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3. Risk and outcome similar for bypass surgery, drug-eluting stents
   04-19-2007 · EurekAlert!
   Drug-eluting stent therapy and bypass surgery for coronary artery disease have about the same risk for a major cardiac event within 30 days after the procedures, researchers reported at the American Heart Association's 8th annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology.
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4. Aspirin may be less effective heart treatment for women than men
   04-27-2007 · EurekAlert!
   A new study shows that aspirin therapy for coronary artery disease is four times more likely to be ineffective in women compared to men with the same medical history.
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5. Bypass Surgery Tops Angioplasty For Sickest Heart Patients
   10-05-2006 · ScienceDaily
   Patients with severe coronary artery disease live longer if they receive coronary artery bypass surgery as their initial treatment instead of artery-opening angioplasty or heart medications, according to a Duke University Medical Center analysis.
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6. Type 1 diabetes and heart disease -- Heavier may mean healthier
   06-23-2007 · EurekAlert!
   Researchers at the University of Pittsburgh Schools of the Health Sciences studying links between an early sign of heart disease called coronary artery calcification and body fat have found that, paradoxically, more fat may have some advantages, at least for people -- particularly women -- who have type 1 diabetes. Cardiovascular complications, including heart disease, are a leading cause of death for people with diabetes, who tend to suffer cardiovascular disease decades earlier than non-diabetics.
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7. Anticlotting drug found to be safe in sickle cell patients
   10-11-2007 · EurekAlert!
   An intravenous "blood thinner" widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have beneficial anti-inflammatory effects, a small study at the University of North Carolina at Chapel Hill School of Medicine has found.
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8. Nationally known VCU cardiologist writes editorial in New England Journal of Medicine
   02-06-2008 · EurekAlert!
   George W. Vetrovec, M.D., chair of cardiology at the Virginia Commonwealth University Medical Center, known nationally for his study and treatment of coronary artery disease, says a new technique for treating blocked coronary arteries shows promise, but is best performed by experienced physicians.
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9. Researchers shed light on genetic factors behind UK's biggest killer
   01-10-2008 · EurekAlert!
   Researchers have discovered a new chromosomal region to be strongly associated with bad cholesterol -- a major cause of coronary heart disease. The finding could pave the way towards new therapies for the diease.
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10. Story ideas from Molecular and Cellular Proteomics
    02-11-2008 · EurekAlert!
    A set of 15 proteins found in urine can distinguish healthy individuals from those who have coronary artery disease, a new study has found.
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