Daily non-political popular news in brief.

Oregon team zeroes in on RNA-binding in myotonic dystrophy

University of Oregon researchers have shed new light on the function of an RNA-regulating protein known as muscleblind, which when it misbehaves and binds to rogue RNA can lead to disease affecting roughly one in 8,000 people.

Read more »

Keywords: oregon, team, zeroes, rna-binding, myotonic, dystrophy, zeroe, rna, binding

« Previous | Next »

Similar news on "Oregon team zeroes in on RNA-binding in myotonic dystrophy":

1. Mouse with myotonic dystrophy type 1 finds RNA binding proteins at heart of problem
   09-05-2007 · EurekAlert!
   A new mouse model for myotonic dystrophy - the most common form of adult-onset muscular dystrophy - helped Baylor College of Medicine researchers show that levels of CUGBP1, a protein that binds and controls the activity of the genetic material RNA, increase early in affected cells of the animals with the disease. This means CUGBP1 plays a key role in the disorder.
   Similar news · Read more »
   
2. RNA-binding protein key to understanding myotonic dystrophy type 1
   10-11-2007 · EurekAlert!
   Increased levels of a protein called CUGBP1 play an important role in the adult-onset form of muscular dystrophy called myotonic dystrophy type 1, said Baylor College of Medicine researchers in a report that appears today in the journal Molecular Cell.
   Similar news · Read more »
   
3. RNA splicing factor implicated in ovarian tumor cell growth
   04-09-2007 · EurekAlert!
   An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers, according to researchers at the University of Illinois at Chicago.
   Similar news · Read more »
   
4. Immune system protein starves 'staph' bacteria
   02-14-2008 · EurekAlert!
   A multi-disciplinary team led by Vanderbilt University investigators has discovered that a protein inside certain immune system cells blocks the growth of "staph" bacteria by sopping up manganese and zinc.The findings, reported Feb. 15 in Science, support the notion that binding metals -- to starve bacteria -- is a viable therapeutic option for treating localized bacterial infections. New treatments are urgently needed to combat antibiotic-resistant forms of staph, such as MRSA.
   Similar news · Read more »
   
5. Regulating Muscle Decline: Small molecules linked to degenerative diseases
   10-20-2007 · Science News Online
   Snippets of RNA that regulate gene activity play a role in muscle-wasting diseases such as muscular dystrophy.
   Similar news · Read more »
   
6. Hairpins for switches
   12-12-2006 · EurekAlert!
   How does an organism know when it must produce a protein and in what amount? Michael Famulok and his team at the University of Bonn have now taken a meaningful step toward a better understanding of this process by successfully producing hairpin-shaped RNA molecules that are able to differentiate between riboswitches in the on and off states.
   Similar news · Read more »
   
7. Advance helps explain stem cell behavior
   11-20-2006 · EurekAlert!
   Biochemists at Oregon State University have developed a new method to identify the "DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ultimately make up all the organs and parts of a living vertebrate animal. The research is an important step towards understanding stem cell behavior and how cellular development is controlled.
   Similar news · Read more »
   
8. RNA interference therapy heals growth deficiency disorder in a live animal
   12-18-2007 · EurekAlert!
   A team of Vanderbilt researchers have demonstrated for the first time that a new type of gene therapy, called RNA interference, can heal a genetic disorder in a live animal.
   Similar news · Read more »
   
9. M. D. Anderson team identifies new oncogene for brain cancer
   07-02-2007 · EurekAlert!
   Research in Proceedings of the National Academy of Sciences transforms biomarker into potential target for therapy. Insulin-like growth factor binding protein 2 is overexpressed in many cancers.
   Similar news · Read more »
   
10. ClC-1 helps mice get a move on
    11-15-2007 · EurekAlert!
    One symptom of myotonic dystrophy is the inability to voluntarily relax the muscles. DM originates from complex genetic mutations that result in abnormalities of several muscle proteins, including ClC-1. A new study, has established that abnormal inclusion of a specific region of the ClC-1 gene in ClC-1 mRNA has a role in the development of disease in mouse models of DM and developed an approach to correct this, eliminating myotonia.
    Similar news · Read more »