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Imaging neural progenitor cells in the living human brain
11-08-2007 · EurekAlert!For the first time, investigators have identified a way to detect neural progenitor cells, which can develop into neurons and other nervous system cells, in the living human brain using a type of imaging called magnetic resonance spectroscopy. The finding, supported by the National Institutes of Health, may lead to improved diagnosis and treatment for depression, Parkinson's disease, brain tumors, and a host of other disorders.
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Keywords: imaging, neural, progenitor, cells, living, human, brain, cell
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- Team of scientists develops non-invasive method to track nerve-cell development in live human brain
11-08-2007 · EurekAlert!
A team of scientists including researchers at Cold Spring Harbor Laboratory have identified and validated the first biomarker that permits neural stem and progenitor cells to be tracked, non-invasively, in the brains of living human subjects. This important advance could lead to significantly better diagnosis and monitoring of brain tumors and a range of serious neurological and psychiatric disorders.
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- SBUMC Researchers First to Image a Biomarker of Neurogenesis
11-09-2007 · Brookhaven National Laboratory
Mirjana Maletic-Savatic, M.D., Ph.D, and co-investigators from Stony Brook University Medical Center, Brookhaven National Laboratory and Cold Spring Harbor Laboratory have discovered a way to image a biomarker of neural stem and progenitor cells (NPCs) in the living human brain. This discovery allows researchers to monitor neurogenesis, the development of nerve tissues.
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- MIT creates 3-D scaffold for growing stem cells
12-26-2006 · EurekAlert!
Stem cells grew, multiplied and differentiated into brain cells on a new three-dimensional scaffold of tiny protein fragments designed to be more like a living body than any other cell culture system.
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- MIT creates 3D scaffold for growing stem cells
12-27-2006 · Massachusetts Institute of Technology (MIT)
An MIT engineer and colleagues report that stem cells grew, multiplied and differentiated into brain cells on their new three-dimensional scaffold of tiny protein fragments designed to be more like a living body than any other cell culture system.
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- 3-D fruit fly images to benefit brain research
09-04-2007 · EurekAlert!
In a paper published on September 5 in the online, open-access journal PLoS ONE, a team led by Mary O'Connell of the MRC Human Genetics Unit describe how they have already used an imaging technique called optical projection tomography (OPT) to image individual cavities within the brain of an aging fly and see the brain deteriorate. The OPT images could help to speed up genetic research into Alzheimer's and other human diseases affecting brain cells.
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- Carnegie Mellon scientists develop fluorescent proteins for live cell imaging, biosensor design
02-06-2008 · EurekAlert!
Scientists at Carnegie Mellon University's Molecular Biosensor and Imaging Center have developed new "fluorogen activating proteins" that will become a key component of novel molecular biosensor technology being created at Carnegie Mellon. The FAPs, which can be used to monitor biological activities of individual proteins and other biomolecules within living cells in real time, are described in the February issue of Nature Biotechnology.
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- Neural stem cell study reveals mechanism that may play role in cancer
09-04-2007 · EurekAlert!
In the dynamic world of the developing brain, neural stem cells give rise to neurons deep within the brain’s fluid-filled ventricles. These newborn neurons then migrate along the stem cell fibers up to the neocortex, the seat of higher cognitive functions. Now, scientists have discovered a key mechanism of this migration -- one that may also play an important role in other developmental processes and diseases, including cancer.
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- Neural stem cells lend the brain a surprising capacity for self-repair
12-14-2006 · EurekAlert!
The brain contains stem cells with a surprising capacity for repair, researchers report in the Dec. 15 issue of the journal Cell, published by Cell Press. The novel insight into the brain's natural ability to heal might ultimately have clinical implications for the treatment of brain damage, according to the researchers.
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- LCT reports major step forward for islet transplantation in diabetes patient
03-29-2007 · EurekAlert!
Living Cell Technologies has published evidence outlining the survival and identification of live porcine islet cells and insulin production in a human patient with diabetes 10 years after he received a micro-encapuslated pig islet cell transplant. The paper outlines how LCT has demonstrated the long-term safety, viability and function of its encapsulated porcine islets in a human patient over an extended period of time, without the use of immunosuppression.
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- Replacing the cells lost in Parkinson disease
12-03-2007 · EurekAlert!
Parkinson disease is caused by the progressive degeneration of dopamine brain cells. Replacing these cells is considered a promising therapeutic strategy. Although DA cell-replacement therapy by transplantation of human fetal mesencephalic tissue has shown promise, limited tissue availability means other sources of these cells are needed. A recent study has described one new source for DA cells that provided marked benefit when transplanted into mice with a PD-like disease.
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