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An Alzheimer's vaccine?

11-11-2007 · EurekAlert!

A new research study from the Oklahoma Medical Research Foundation shows that immunization could offer a way to blunt or even prevent the deadly, memory-robbing disease.

Keywords: alzheimer, vaccine

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JCI table of contents -- June 1, 2007
06-01-2007 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, June 1, 2007, in the JCI, including: Pregnant mom’s exposure to flu vaccine kick-starts fetal immune system; Dietary supplementation with enzyme reverses some kidney disease; Don’t judge a book by its cover: Interleukin-1beta turns out to be helpful in Alzheimer's disease; HIF provides a link between blood and bone development; and others.
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Transdermal vaccine effective in treating Alzheimer's disease in mouse model
01-22-2007 · EurekAlert!
A novel needle-free vaccine approach was found safe and effective in clearing brain-damaging plaques from mice bred to develop Alzheimer's disease. The transdermal vaccination may offer a simple, noninvasive way of preventing or treating Alzheimer'swith less potential for adverse immune reactions.
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Alzheimer's disease diagnosed 100 years ago today
11-03-2006 · EurekAlert!
One hundred years after the first diagnosis of Alzheimer's disease Nov. 3, 1906, researchers at the Yerkes National Primate Research Center, Emory University, are focusing on neuroscience, immunology and vaccine research to better understand how AD develops and progresses as well as to advance the treatment and prevention of this progressive brain disorder. AD, which currently affects 20 million Americans, gradually destroys memory and the ability to learn, reason, make judgments and communicate.
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Paving the way toward a vaccine against Alzheimer's disease
06-21-2007 · EurekAlert!
Scientists have provided new details about how proteins used to destroy bacteria and viruses may help treat Alzheimer's disease. Gunnar K. Gouras, associate professor of neurology and neuroscience at Weill Medical College of Cornell University, New York, and colleagues provide new insights into how these proteins, called antibodies, reduce the main hallmarks of Alzheimer's disease and raise hopes for a vaccine against the disease.
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Vaccine thwarts the tangles of Alzheimer's
08-21-2007 · EurekAlert!
A new study by NYU Medical Center researchers shows for the first time that the immune system can combat the pathological form of tau protein, a key protein implicated in Alzheimer's disease. The researchers, led by Einar Sigurdsson Ph.D., assistant professor of psychiatry and pathology at New York University School of Medicine, created a vaccine in mice that suppresses aggregates of tau. The protein accumulates into harmful tangles in the memory center of the brains of Alzheimer's patients.
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Key Function Of Nervous System Enzyme Found; Impact On Drug Development Against Alzheimer's
09-29-2006 · ScienceDaily
Ever since scientists first elucidated the molecular mechanisms underlying the pathology and loss of nerve cells in Alzheimer's disease, drug companies have been working to develop drugs which will inhibit the outbreak of this severe form of dementia. Now researchers in Munich and Berlin (Germany) have discovered that an enyzme which has a central causal role in Alzheimer's disease happens also to have a key function in the normal development of the nervous system. This enzyme, beta-secretase or BACE1, ensures that nerve fibers (axons) are adequately isolated with sheaths of myelin, enabling rapid conduction of electrical impulses, as well as preventing short-circuits, akin to plastic insulation on electrical wires.
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Hope remains for Alzheimer's sufferers
10-30-2006 · EurekAlert!
The National Institute of Clinical Excellence (NICE), who last week rejected appeals to allow patients with mild Alzheimer's to receive the life-changing medication donepezil (Aricept®), will hopefully re-appraise their decision in three-years time, according to neurologist Professor Robert Kerwin in an article published in the November issue of the medical journal Future Neurology.
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New studies on Alzheimer's, autism, nicotine addiction and depression highlight annual meeting
11-29-2006 · EurekAlert!
The 2006 American College of Neuropsychopharmacology annual meeting will feature hundreds of new studies on brain and behavior from the world's leading scientists. Presentations include innovative research on potential new treatments for Alzheimer's disease, autism, nicotine addiction and treatment resistant depression.
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New imaging technique identifies people-at-risk for Alzheimer's disease
12-20-2006 · EurekAlert!
UCLA researchers used innovative brain scan technology with a new imaging molecule, invented at UCLA, to show that abnormal brain protein deposits that define Alzheimer's disease can be detected in people with mild cognitive impairment, a condition affecting 15-20 million Americans that increases risk for developing Alzheimer's disease. The new imaging technique helped researchers track disease progression over a two-year period and may be helpful in detecting pre-Alzheimer's conditions.
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Researchers discover genetic cause for word-finding disease
01-15-2007 · EurekAlert!
Northwestern University researchers have discovered a genetic cause of a mysterious neurological disease in which people have trouble recalling and using words. The illness, Primary Progressive Aphasia, differs from Alzheimer's Disease in which a person's memory becomes impaired. In PPA, which can begin in the 40's and 50's, people eventually lose the ability to express themselves and understand speech. Although people lose the ability to communicate, they are still able to perform complicated tasks.
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