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Connection between startled response and schizophrenia
11-12-2007 · EurekAlert!The search for responsible genes for prepulse inhibition, a measure deemed to be a biological trait in schizophrenia, has exposed a gene encoding essential fatty acid-binding protein.
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Keywords: connection, startled, response, schizophrenia
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- Study finds role of mid-brain in integrating heart and respiratory response to exercise
04-29-2007 · EurekAlert!
Oxford University researchers recently examined several deep brain nuclei during exercise and have concluded that the periaqueductal grey area (PAG), the small-celled gray matter adjoining or surrounding the cerebral aqueduct and the third ventricle in the midbrain, contains the greatest number of neural changes in connection with anticipation of exercise. The findings provide direct evidence implicating the PAG as a key area of the brain's circuitry's affecting cardiorespiratory response to exercise.
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- New dopamine brain target discovered
01-23-2007 · EurekAlert!
A team of Canadian researchers, lead by Dr. Susan George and Dr. Brian O'Dowd at the Center for Addiction and Mental health, discovered a Gq/11-coupled signalling unit that triggers a calcium signal. This novel target is turned on by stimulating D1 and D2 dopamine receptors. This is the first time that a direct connection between dopamine and calcium signals has been reported. This data has significant implications for schizophrenia.
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- Molecular 'foreman' discovered for brain wiring
11-21-2007 · EurekAlert!
Researchers have identified a master regulatory molecule that is responsible for triggering the remodeling of neuronal connections that is critical for learning. Malfunctioning of the connection-remodeling machinery that they identified may also play a role in mental retardation, schizophrenia, and drug addiction. Thus, said the researchers, knowledge of the machinery could lead to insights into those disorders. Peter Penzes and colleagues published their findings in the Nov. 21, 2007, issue of the journal Neuron, published by Cell Press.
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- Scientists identify gene that may indicate predisposition to schizophrenia
01-24-2007 · EurekAlert!
In a study from the January issue of the American Journal of Human Genetics, a research team lead by Xinzhi Zhao and Ruqi Tang (Shanghai Jiao Tong University) present evidence that genetic variation may indicate predisposition to schizophrenia. Specifically, their findings identify the chitinase 3-like 1 gene as a potential schizophrenia-susceptibility gene and suggest that the genes involved in biological response to adverse conditions are likely linked to schizophrenia.
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- Some antipsychotic drugs may be missing their mark
12-31-2007 · EurekAlert!
Drugs that treat depression and schizophrenia might not be triggering the most appropriate response in brain cells, new research suggests. This study examined the early chemical events that happen when a particular serotonin receptor on brain cells is stimulated by serotonin and by a hallucinogenic agent thought to mimic serotonin. The findings show that although both compounds activate this receptor, they trigger different chemical pathways inside the cell.
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- UVA researchers explain cell response to skin-damaging UV rays
10-01-2007 · EurekAlert!
Researchers at the University of Virginia Health System have published a new study that helps scientists around the world expand the body of knowledge on how cells protect themselves (or not) from DNA damage caused by UV rays. Their study reveals part of a 'simple switch' mechanism inside cells, triggered by UV exposure from the sun, that helps our cells survive and thrive after being exposed. This mechanism involves an unanticipated connection between several proteins in the cell, the researchers discovered.
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- Genetic variant predicts antipsychotic response for schizophrenia patients by ethnicity
01-08-2008 · EurekAlert!
Schizophrenia is a developmental disorder with a large genetic component contributing to increased risk. Available antipsychotic medications treat some of the symptoms of schizophrenia, but are typically effective in only a subset of patients.
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- A genetic variant increases the risk of developing schizophrenia in women
02-14-2008 · EurekAlert!
A complete scan of the human genome has revealed that a genetic variant in the Reelin gene increases the risk of developing schizophrenia in women only. Researchers from the Hebrew University of Jerusalem and the University of Oxford, who conducted the study in the Ashkenazi Jewish population, confirmed their findings by establishing a multinational collaboration that included populations and researchers from the United Kingdom, Ireland, United States, and China. Their research is published in the February issue of the open-access journal PLoS Genetics.
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- Why would Cheerios sponsor a NASCAR race?
10-18-2006 · EurekAlert!
Why would brands like Sue Bee honey and Cheerios cereal sponsor a NASCAR race? While most people can quickly see the relationship between a sponsor that makes tires or motor oil, not all corporate sponsors "fit" NASCAR in such an obvious way. In the first study to research the benefits of event sponsorship for brands that don't seem to fit with a particular event, researchers from the University of Queensland (Australia) reveal a relatively easy way for marketers to overcome a tenuous connection.
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- Talk on cheese gives a taste of 'terroir'
01-02-2007 · Massachusetts Institute of Technology (MIT)
Plates of handcrafted cheeses, carefully arranged for identification purposes, were distributed to an eager group of auditors last month, in connection with a talk given by Heather Paxson, lecturer in anthropology.
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