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Cell transplants may improve severe urinary incontinence

Severe urinary incontinence can be caused by urethral sphincter muscle deficiency, often associated with trauma during childbirth, prostate surgery, or aging. When skeletal myoblasts -- progenitor muscle cells with the potential to develop into muscle fiber -- were transplanted into female rats suffering from urethral sphincter deficiency, transplanted muscle cells helped increase urethral pressure, improving incontinence. Implanting myoblasts could be a potential innovative therapy for urethral deficiencies that lead to human incontinence.

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Keywords: cell, transplants, improve, severe, urinary, incontinence, transplant

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