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STEP HIV vaccine study to be unblinded
11-13-2007 · EurekAlert!Merck & Co., Inc. and the HIV Vaccine Trials Network today announced that study volunteers in the STEP study of Merck's HIV vaccine will be told whether they received vaccine or placebo, and all study volunteers will be encouraged to continue to return to their study sites on a regular basis for ongoing risk reduction counseling and study-related tests.
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Keywords: step, hiv, vaccine, study, unblinded
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- The release of new data from the HVTN 502 HIV vaccine study
11-07-2007 · EurekAlert!
The new analyses revealed today from the STEP HIV vaccine clinical trial are both disappointing and puzzling. At this time, the data offer no clear explanations as to why the vaccine showed no measurable efficacy or why among individuals with background immunity to the adenovirus vector, there were more HIV infections in the vaccinees as compared to those in the placebo group. Analyses of the STEP data are continuing, and it will take some time before we fully understand these results.
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- Virus used to create experimental HIV vaccines directly impairs the immune response
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- Chronic HIV-1 infection frequently fails to protect against superinfection
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