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Human embryonic stem cells derived from preimplantation genetically diagnosed embryos
11-14-2007 · EurekAlert!A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
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Keywords: human, embryonic, stem, cells, derived, preimplantation, genetically, diagnosed, embryos, cell, embryo
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- Human embryonic stem cell -- derived bone tissue closes massive skull injury
12-02-2007 · EurekAlert!
There are mice in Baltimore whose skulls were made whole again by bone tissue grown from human embryonic stem cells. Healing critical-size defects, which would not otherwise heal on their own, in intramembraneous bone, the flat bone type that forms the skull, is a vivid demonstration of new techniques devised by researchers using hESCs for tissue regeneration.
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- Human embryonic stem cell lines created that avoid immune rejection
12-20-2007 · EurekAlert!
In a groundbreaking experiment published in Cloning & Stem Cells, scientists from International Stem Cell Corp. derived four unique embryonic stem cell lines that open the door for the creation of therapeutic cells that will not provoke an immune reaction in large segments of the population. The stem cell lines are "HLA-homozygous," meaning that they have a simple genetic profile in the critical areas of the DNA that code for immune rejection.
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- Reprogrammed adult cells treat sickle-cell anemia in mice
12-06-2007 · EurekAlert!
This is the first proof of principle for using adult cells reprogrammed to an embryonic-stem-cell-like state, combined with gene and cell therapy, for successful disease treatment in mice. Similar "induced pluripotent stem cells" were recently derived with human cells.
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- UC Davis researchers find evidence of mature heart cell potential in embryonic stem cells
11-27-2007 · EurekAlert!
In a new study, UC Davis researchers report thefirst functional evidence that heart cells derived from human embryonicstem cells exhibit one of the most critical properties of mature adultheart cells, an important biological process called excitation-contractioncoupling.
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- UCLA stem cell scientists reprogram human skin cells into embryonic stem cells
02-11-2008 · EurekAlert!
UCLA stem cell scientists have reprogrammed human skin cells into cells with the same unlimited properties as embryonic stem cells without using embryos or eggs.
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- UCLA scientists produce functioning neurons from human embryonic stem cells
08-07-2007 · EurekAlert!
Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem cells a highly pure, large quantity of functioning neurons that will allow them to create models of and study diseases such as Alzheimer's, Parkinson's, prefrontal dementia and schizophrenia.
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- Geron Demonstrates hESC-derived cardiomyocytes improve heart function after myocardial infarction
08-27-2007 · EurekAlert!
Geron Corporation (Nasdaq: GERN) today reported its scientists and collaborators have demonstrated that human embryonic stem cell (hESC)-derived cardiomyocytes improve heart function when transplanted after myocardial infarction.
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- Scientists overcome obstacles to stem cell heart repair
12-12-2007 · EurekAlert!
Scientists have overcome two significant obstacles on the road to harnessing stem cells to build patches for damaged hearts. Presenting the research at a UK Stem Cell Initiative conference the researchers will explain how they have made significant progress in maturing beating heart cells derived from embryonic stem cells and in developing the physical scaffolding that would be needed to hold the patch in place in the heart in any future clinical application.
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- Parkinson's approach with stem cells a promising first step
12-01-2006 · EurekAlert!
Brain cells derived from human embryonic stem cells improved the condition of rats with Parkinson's-like symptoms dramatically, but the treatment caused a significant problem -- the appearance of brain tumors -- that scientists are now working to solve. The study is featured on the cover of the November issue of Nature Medicine.
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- Simple recipe turns human skin cells into embryonic stem cell-like cells
11-20-2007 · EurekAlert!
A simple recipe -- including just four ingredients -- can transform adult human skin cells into cells that resemble embryonic stem cells, researchers report in an immediate early publication of the journal Cell, a publication of Cell Press. The converted cells have many of the physical, growth and genetic features typically found in embryonic stem cells and can differentiate to produce other tissue types, including neurons and heart tissue, according to the researchers.
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