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Purdue research finds similarities in dog, human breast cancer pre-malignant lesions
11-15-2007 · EurekAlert!Pre-malignant mammary lesions in dogs and humans display many of the same characteristics, a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine.
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Keywords: purdue, research, similarities, dog, human, breast, cancer, pre-malignant, lesions, similarity, pre, malignant, lesion
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- Small RNAs can prevent spread of breast cancer
01-09-2008 · EurekAlert!
Howard Hughes Medical Institute researchers have identified small pieces of ribonucleic acid that suppress the spread of breast cancer to the lungs and bone. The new research shows that the most invasive and aggressive human breast cancer tumors are missing three critical microRNA molecules. When the researchers put those molecules back into human breast cancer tumors in mice, the tumors lost their ability to spread.
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- Study: HPV test beats Pap in detecting cervical cancer
10-17-2007 · EurekAlert!
A new study led by McGill University researchers shows that the human papillomavirus screening test is far more accurate than the traditional Pap test in detecting cervical cancer. The first round of the Canadian Cervical Cancer Screening Trial concluded that the HPV test's ability to accurately detect pre-cancerous lesions without generating false negatives was 94.6 percent, as opposed to 55.4 percent for the Pap test.
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- Cell response to stress signals predicts tumors in women with common pre-breast cancer
11-12-2007 · EurekAlert!
A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, noninvasive form of pre-malignant breast cancer -- ductal carcinoma in situ, or DCIS.
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- Newly created cancer stem cells could aid breast cancer research
08-13-2007 · EurekAlert!
Scientists have created breast cancer stem cells in culture by isolating and transforming a particular population of cells from normal human breast tissue. After being injected with just 100 of these transformed cells, mice develop tumors that metastasize. When scientists performed the same transformation process on a slightly different population of cells from the identical human breast tissue, the resulting cancer cells were 10,000 times less potent as tumor initiators and could not move to other tissues.
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- Indian medicinal plant Acanthus ilicifolius may combat liver cancer
01-16-2008 · EurekAlert!
Cancer chemoprevention is an active measure to limit/retard the progression and pathogenesis of malignancy. Herbal preparations constitute an important component of indigenous/traditional medicines. A study led by Prof. Malay Chatterjee from Jadavpur University, India reported the potential chemopreventive efficacy of an Indian medicinal plant Acanthus ilicifolius in preventing liver DNA damage and in remodeling hepatocellular malignant lesions in an animal model, which may have an ultimate benefit to human beings in near future.
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- Profiling of cancer genes may lead to better and earlier detection
12-25-2006 · EurekAlert!
A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers -- lung, breast, prostate and colon cancer.
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- Study offers innovative profile of enzyme that aids tumor growth
10-20-2006 · EurekAlert!
Using an innovative profiling strategy, scientists at the Scripps Research Institute have characterized an enzyme that is "highly elevated" in aggressive human tumor cells. When the enzyme, KIAA1363, was inactivated, it impaired tumor growth and migration in both ovarian and breast cancer cells, suggesting that inhibitors of this enzyme may prove valuable in the treatment of multiple types of cancer.
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- Profiling of cancer genes may lead to better and earlier detection of solid human cancers
12-27-2006 · UT Southwestern Medical Center
A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers — lung, breast, prostate and colon cancer.
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- New model to aid pancreatic cancer research
11-14-2006 · EurekAlert!
Vanderbilt-Ingram Cancer Center researchers have developed a new animal model for pancreatic cancer that exhibits a high degree of similarity to human tumors.
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- International studies show high efficacy for HPV vaccine
05-31-2007 · EurekAlert!
A new vaccine aimed at preventing cervical cancer is nearly 100 percent effective against the two types of the human papillomavirus responsible for most cases of cervical cancerСstrains 16 and 18. Researchers combined and analyzed the data from four randomized trials that involved 20,583 women ages 15 to 26 from more than two dozen countries. Researchers found that the prophylactic administration of the vaccine was highly effective in preventing pre-malignant changes of the cervix.
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