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Blood clotting protein linked to rheumatoid arthritis

11-16-2007 · EurekAlert!

Researchers at Cincinnati Children's have issued the first study showing that a protein involved in blood clotting (fibrin), also plays an important role in the development of rheumatoid arthritis. Inflammatory joint disease appears to be driven by the engagement of inflammatory cells with fibrin matrices through a specific integrin receptor, aMD2. Researchers suggest that therapies designed to interrupt the localized interaction of inflammatory cells and fibrin may help arthritis patients.

Keywords: blood, clotting, protein, linked, rheumatoid, arthritis, arthriti

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