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MIT: 'Micro' livers could aid drug screening
11-18-2007 · EurekAlert!MIT researchers have devised a novel way to create tiny colonies of living human liver cells that model the full-sized organ. The work could allow better screening of new drugs that are potentially harmful to the liver and reduce the costs associated with their development.
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Keywords: mit, micro, livers, aid, drug, screening, liver
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- 'Micro' livers could aid drug screening
11-19-2007 · Massachusetts Institute of Technology (MIT)
MIT researchers have devised a novel way to create tiny colonies of living human liver cells that model the full-sized organ. The work could reduce costs and allow better screening of new drugs that are potentially harmful to the liver.
Similar news · Read more »
- Mice, men make livers differently
05-21-2007 · EurekAlert!
Scientists often study mice as a model for human biology and disease, because their basic biological processes are assumed to be essentially the same as those of humans. But now, a team of MIT researchers has uncovered a surprising difference. In a study of gene regulation in mouse and human liver cells, they found that master regulatory proteins function in very different ways in mice and humans.
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- A 'micro pharmacy' inside
02-11-2008 · Massachusetts Institute of Technology (MIT)
A new thin-film coating developed at MIT can deliver controlled drug doses to specific targets in the body following implantation, essentially serving as a "micro pharmacy." The film could eventually be used to deliver drugs for many diseases.
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- MIT develops thin-film 'micro pharmacy'
02-11-2008 · EurekAlert!
A new thin-film coating developed at MIT can deliver controlled drug doses to specific targets in the body following implantation, essentially serving as a "micro pharmacy."
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- Incidence of Fatty Liver Disease rises as obesity in children increases
03-15-2007 · EurekAlert!
As part of a national multicenter research network, Indiana University School of Medicine researchers are looking at Vitamin E and at metformin, a drug used to treat Type II diabetes, as possible therapies for Fatty Liver Disease in 8 to 17 year olds. Fatty Liver Disease may exist in 15 percent or more of obese children.
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- MIT researchers reverse symptoms in mice of leading inherited cause of mental retardation
06-25-2007 · EurekAlert!
Researchers at the Picower Institute at MIT have, for the first time, reversed symptoms of mental retardation and autism in mice. The study may lead to new drug therapies for a leading inherited cause of mental retardation (Fragile X Syndrome) and some types of autism.
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- Anti-obesity drug may prevent and treat obesity-related liver disease
07-02-2007 · EurekAlert!
A new study on the effect of the anti-obesity drug rimonabant on liver function in obese rats found that it reduced markers of liver damage, decreased levels of pro-inflammatory proteins, and improved lipid profiles.
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- Fantastic voyage: Drug delivery by a nanoparticle
02-13-2008 · Massachusetts Institute of Technology (MIT)
An image portrays targeted nanoparticles delivering high doses of chemotherapy to cancer cells. A team including MIT Institute Professor Robert Langer has demonstrated the precision required to engineer a nanoparticle that is effective in targeted drug delivery.
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- Mayo Clinic Proceedings contributors discuss impact of donor organ allocation system
02-06-2008 · EurekAlert!
Liver transplant is a life saving treatment option for people with end-stage liver disease. Unfortunately, the need for donor livers far exceeds the supply. Each year only about one-third of people who need a donor liver will receive one, and some patients die while waiting. In the February issue of Mayo Clinic Proceedings, physicians explore how the current system for allocating donor organs in the United States affects outcomes for patients with end-stage liver disease.
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- ASU discovery may aid counter-terrorism efforts
10-12-2006 · EurekAlert!
The thwarted 2006 London airline bomb plot not only heightened summer travel fears and created new passenger screening inconveniences, but also greatly underscored the urgent need for improved national security measures. Now, professor Joe Wang, director of the Center for Biosensors and Bioelectronics at the Biodesign Institute at Arizona State University, has developed a highly sensitive technology to rapidly detect liquid peroxide explosives in as little as 15 seconds.
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