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'Micro' livers could aid drug screening
11-19-2007 · Massachusetts Institute of Technology (MIT)MIT researchers have devised a novel way to create tiny colonies of living human liver cells that model the full-sized organ. The work could reduce costs and allow better screening of new drugs that are potentially harmful to the liver.
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Keywords: micro, livers, aid, drug, screening, liver
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Similar news on "'Micro' livers could aid drug screening":
- MIT: 'Micro' livers could aid drug screening
11-18-2007 · EurekAlert!
MIT researchers have devised a novel way to create tiny colonies of living human liver cells that model the full-sized organ. The work could allow better screening of new drugs that are potentially harmful to the liver and reduce the costs associated with their development.
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- Anti-obesity drug may prevent and treat obesity-related liver disease
07-02-2007 · EurekAlert!
A new study on the effect of the anti-obesity drug rimonabant on liver function in obese rats found that it reduced markers of liver damage, decreased levels of pro-inflammatory proteins, and improved lipid profiles.
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- Mayo Clinic Proceedings contributors discuss impact of donor organ allocation system
02-06-2008 · EurekAlert!
Liver transplant is a life saving treatment option for people with end-stage liver disease. Unfortunately, the need for donor livers far exceeds the supply. Each year only about one-third of people who need a donor liver will receive one, and some patients die while waiting. In the February issue of Mayo Clinic Proceedings, physicians explore how the current system for allocating donor organs in the United States affects outcomes for patients with end-stage liver disease.
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- ASU discovery may aid counter-terrorism efforts
10-12-2006 · EurekAlert!
The thwarted 2006 London airline bomb plot not only heightened summer travel fears and created new passenger screening inconveniences, but also greatly underscored the urgent need for improved national security measures. Now, professor Joe Wang, director of the Center for Biosensors and Bioelectronics at the Biodesign Institute at Arizona State University, has developed a highly sensitive technology to rapidly detect liquid peroxide explosives in as little as 15 seconds.
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- Incidence of Fatty Liver Disease rises as obesity in children increases
03-15-2007 · EurekAlert!
As part of a national multicenter research network, Indiana University School of Medicine researchers are looking at Vitamin E and at metformin, a drug used to treat Type II diabetes, as possible therapies for Fatty Liver Disease in 8 to 17 year olds. Fatty Liver Disease may exist in 15 percent or more of obese children.
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- Bacterial walls come tumbling down
03-09-2007 · EurekAlert!
The first detailed images of an elusive drug target on the outer wall of bacteria may provide scientists with enough new information to aid design of novel antibiotics. The drugs are much needed to treat deadly infections initiated by Staphylococcus aureus and other bacterial pathogens.
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- Drug treats 'water intoxication' faster, more effectively
11-14-2006 · EurekAlert!
Results of the two largest studies on hyponatremia found that the investigational drug tolvaptan treated hyponatremia -- water intoxication -- more effectively than available treatments. These studies, presented by a researcher from Northwestern University, proved that hyponatremia can be treated with an oral drug that has no significant side effects. Hyponatremia is a relatively common electrolyte disorder. It affects a wide spectrum of patients including those with liver problems, heart failure and the elderly. It also may affect marathon runners.
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- New treatment increases life time expectancy of patients suffering from advanced liver cancer
06-04-2007 · EurekAlert!
A clinical trial led and coordinated by Hospital Clнnic-IDIBAPS, using a drug named Sorafenib, revolutionizes the reality of patients suffering from advanced liver cancer. The results increase overall survival of treated patients by 44 percent in comparison to the control group. The results have been hand selected to be included on the "Best of ASCO" program.
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- New mouse model closely mimics human cancers
05-24-2007 · EurekAlert!
A team led by Dana-Farber Cancer Institute scientists has developed a more human-like mouse model of cancer they say will aid the search for cancer-causing genes and improve the predictive value of laboratory drug testing.
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- Hair-growth drug artificially lowers PSA levels in prostate cancer screening, study finds
12-04-2006 · EurekAlert!
The popular hair-growth drug finasteride, taken by millions of balding men, artificially lowers the results of the prostate-specific antigen test, the standard screening test for prostate cancer, a multicenter study has found.
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