science top stories popular news  

Daily non-political popular news in brief.

New study finds blood-spinal cord barrier compromised in mice with ALS

11-20-2007 · EurekAlert!

The blood-spinal cord barrier is functionally impaired in areas of motor neuron damage in mice modeling amyotrophic lateral sclerosis, report researchers at the University of South Florida Center for Aging and Brain Repair. The barrier disruption was found in mice at both early and late stages of ALS, a progressive neurodegenerative disease affecting nerve cells in the brain and the spinal cord. The study appears in the online, open-access journal PLoS ONE.

Read more »

Keywords: study, blood-spinal, cord, barrier, compromised, mice, als, blood, spinal

« Previous | Next »

Similar news on "New study finds blood-spinal cord barrier compromised in mice with ALS":

  1. Protein inhibitor tangles with Alzheimer's disease
    02-15-2007 · EurekAlert!
    A hallmark of Alzheimer's disease (AD) is the abnormal accumulation of phosphorylated forms of a protein known as tau. In a new study, Mayo Clinic researchers have now shown in mice that a drug that inhibits the function of the protein Hsp90 (EC102) reduces the amount of phosphorylated tau in the brain. Unlike many drugs, EC102 is able to cross the blood-brain barrier, making it a highly promising therapeutic candidate for AD.
    Similar news · Read more »
  2. Human stem cells delay start of Lou Gehrig's disease in rats
    10-15-2006 · EurekAlert!
    Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life. The grafted stem cells develop into nerve cells that make substantial connections with existing nerves and do not themselves succumb to Lou Gehrig's, also known as amyotrophic lateral sclerosis (ALS). The study is published in this week's issue of Transplantation.
    Similar news · Read more »
  3. Mayo Clinic clarifies diagnosis for serious blood vessel disease of brain and spinal cord
    10-18-2007 · EurekAlert!
    Mayo Clinic has clarified the methods of diagnosis and optimal management of a rare and little-understood blood vessel disease of the brain and spinal cord that often leads to stroke or death. Primary central nervous system vasculitis can best be identified through a combination of diagnostic techniques consisting of angiography, brain biopsy and other laboratory studies.
    Similar news · Read more »
  4. Drug that lowers blood pressure might help prevent Alzheimer's disease
    10-25-2007 · EurekAlert!
    Alzheimer's disease is a neurodegenerative disease that is the most common form of dementia. Recent evidence indicates that some drugs used to treat high blood pressure might reduce the risk of developing AD. In a new study, the antihypertensive medication valsartan has been shown to reduce AD-like disease in mice.
    Similar news · Read more »
  5. Researchers take first steps towards spinal cord reconstruction following injury
    11-12-2007 · EurekAlert!
    A new study has identified what may be a pivotal first step towards the regeneration of nerve cells following spinal cord injury, using the body's own stem cells.
    Similar news · Read more »
  6. Human Stem Cells Delay Start Of Lou Gehrig's Disease In Rats
    10-15-2006 · ScienceDaily
    Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life. The grafted stem cells develop into nerve cells that make substantial connections with existing nerves and do not themselves succumb to Lou Gehrig's, also known as amyotrophic lateral sclerosis (ALS). The study is published in this week's issue of Transplantation.
    Similar news · Read more »
  7. Jefferson immunology researchers show blood-brain barrier damage could affect MS severity
    04-05-2007 · EurekAlert!
    Immunology researchers at the Kimmel Cancer Center at Jefferson studying a multiple sclerosis (MS)-like disease in mice have shown that the amount of "damage" to the central nervous system’s protective blood-brain barrier -- in essence, opening it -- almost always correlates to the severity of the disease. The findings can be used for testing potential MS therapies and for better understanding the role of the blood-brain barrier in disease processes.
    Similar news · Read more »
  8. Combination therapy reduces tumor resistance to radiation
    06-07-2007 · EurekAlert!
    Radiation is used to treat a variety of tumors as it causes hypoxia and tumor cell death. Recently, radiation-induced hypoxia was shown to trigger tumor resistance to radiation via the activation of new blood vessel formation (angiogenesis). In a new JCI study, researchers show that a combination of radiation treatment and the use of angiogenesis inhibitors such as canstatin is able to overcome HIF-1-dependent tumor survival and increase tumor cell death in mice.
    Similar news · Read more »
  9. Cord blood may preserve insulin levels in children with type 1 diabetes
    06-26-2007 · EurekAlert!
    It is feasible to use a patient's own cord blood stem cells to neutralize the body's autoimmune attack on the pancreas and help restore the organ's ability to make insulin, University of Florida researchers have discovered. The finding from a small pilot study is a step toward better treatments for diabetes.
    Similar news · Read more »
  10. Compound in broccoli could boost immune system, says new study
    08-20-2007 · EurekAlert!
    A compound found in broccoli and related vegetables may help boost the immune system, according to a new UC-Berkeley-led study. Researchers found that mice fed mice a solution of the compound, 3,3'-diindolylmethane, had increased blood levels of cytokines -- proteins which help regulate the cells of the immune system -- and were better able to clear reoviruses from their intestines.
    Similar news · Read more »