Daily non-political popular news in brief.
A key antibody, IgG, links cells' capture and disposal of germs
11-13-2006 · EurekAlert!Scientists have found a new task managed by the antibody that's the workhorse of the human immune system: Inside cells, Immunoglobulin G (IgG) helps bring together the phagosomes that corral invading pathogens and the potent lysosomes that eventually kill off the germs.
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Keywords: key, antibody, igg, links, cells, capture, disposal, germs, link, cell, germ
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- Carnegie Mellon scientists find key HIV protein makes cell membranes bend more easily
07-25-2007 · EurekAlert!
Carnegie Mellon University scientists have made an important discovery that helps to explain why HIV enters immune cells with ease. They found that after HIV docks onto a host cell, it dramatically lowers the energy required for a cell membrane to bend, making it easier for the virus to infect immune cells. The finding will provide vital data to conduct future computer simulations of HIV dynamics to help further drug discovery and prevent deadly infections.
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- Penn Veterinary Medicine report new strategy to create genetically-modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- JCI table of contents -- May 17, 2007
05-17-2007 · EurekAlert!
This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, May 17, 2007, in the JCI, including: Role of TRPM8 in the development of prostate cancer; Blocking aggrecanase-2 activity prevents cartilage erosion in arthritis; Keeping red blood cells hydrated in sickle cell disease; Enzymes and exercise curb muscle insulin resistance; Endothelial progenitor cells mend vessel damage with a little help from EphB4; and others.
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- Weill Cornell team identifies potential new cancer drug target
06-21-2007 · EurekAlert!
Research led by scientists at Weill Cornell Medical College has uncovered two new potential points of vulnerability on a key cancer-promoting protein, called XIAP. Drugs that target either of these activities could help push cancer cells back into a more regular programmed cell death and thereby reduce or eliminate tumors.
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- Penn Veterinary Medicine report new strategy to create genetically modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Cilia: small organelles, big decisions
10-03-2007 · EurekAlert!
Johns Hopkins researchers say they have figured out how human and all animal cells tune in to a key signal, one that literally transmits the instructions that shape their final bodies. It turns out the cells assemble their own little radio antenna on their surfaces to help them relay the proper signal to the developmental proteins "listening" on the inside of the cell.
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- Pourquié lab links beta-catenin gradient to process of somite formation
12-27-2007 · EurekAlert!
The Stowers Institute's Pourquié Lab has demonstrated the importance of Beta-catenin, a key component of the Wnt-signaling pathway in the process of somite formation. The work has been published on the Web site of Nature Cell Biology and will appear in a future print issued. It was conducted using a novel real-time imaging technology.
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- Autism risk higher in people with gene variant
01-10-2008 · EurekAlert!
This study strengthens evidence that a gene, CNTNAP2, is involved in autism, and suggests that the link is strongest when a variation in the gene is inherited from moms, rather than dads. The gene encodes a protein that's known to mediate interactions between brain cells and that appears to enable a crucial aspect of brain-cell development. A gene variant that altered either of these activities could have significant impact.
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- St. Jude researchers identify key genetic trigger of acute myeloid leukemia
11-26-2007 · EurekAlert!
A gene called N-Myc leads a double life in certain white blood cells, helping to trigger a cancer called acute myeloid leukemia (AML) under some conditions while triggering apoptosis, or cell suicide, under other conditions, according to results of a mouse study done by investigators at St. Jude Children's Research Hospital.
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- Cancer stem cell marker also drives transcription in normal cells
01-17-2008 · EurekAlert!
New research links the recently discovered function of a multi-faceted transcriptional complex to control of gene expression in both normal cells and cancer stem cells...
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