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Levels of prion protein in brain may not be reliable marker for disease
11-30-2007 · EurekAlert!Rapid diagnostic testing used to check for the presence of prion diseases such as "mad cow disease" might fail to identify some highly infectious samples, researchers have found.
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Keywords: levels, prion, protein, brain, reliable, marker, disease, level
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11-29-2006 · Brookhaven National Laboratory
Results from a brain-imaging study conducted at the U.S. Department of Energy's Brookhaven National Laboratory in collaboration with Mount Sinai School of Medicine in New York indicate that levels of a brain protein proposed as a diagnostic marker for attention-deficit hyperactivity disorder (ADHD) are not positively correlated with the disease. In fact, the study found lower levels of these "dopamine transporter" proteins in certain brain regions of ADHD patients compared with controls.
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- Prion disease treatable if caught early
01-31-2007 · EurekAlert!
Studies in mice have indicated that the effects of prion disease could be reversed if caught early enough. The researchers said that their findings support developing early treatments that aim to reduce levels of prion protein in the brains of people with prion disease. Also, they said that their findings suggest testing the efficacy of treatments in a new way: by analyzing their cognitive effects in prion-infected mice.
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08-16-2007 · EurekAlert!
Scientists have discovered a new protein that may offer fresh insights into brain function in mad cow disease
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12-01-2006 · EurekAlert!
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- Serum carcinoembryonic antigen level can reflect adrenal adenoma
11-21-2007 · EurekAlert!
Serum carcinoembryonic antigen level is widely used as a reliable tumor marker in cancer patients. Previous reports have demonstrated that CEA level is rarely elevated in benign disease, and to our knowledge there have been no reports of CEA-producing benign adrenal tumors. Recently, Dr. Hori and colleagues presented the first case of carcinoembryonic antigen-producing adrenal adenoma, and discussed their techniques of laparoscopic surgery.
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08-12-2007 · EurekAlert!
Scientists have shown how the body's natural way of ridding the body of the toxic protein amyloid-beta is flawed in people with the disease. Then the team demonstrated an experimental method in mice to fix the process, dramatically reducing the levels of the toxic protein in the brain and halting symptoms.
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- Brown team finds crucial protein role in deadly prion spread
01-23-2007 · EurekAlert!
Brown University biologists have made another major advance toward understanding the deadly work of prions, the culprits behind fatal brain diseases such as mad cow and their human counterparts. In new work published online in PLoS Biology, researchers show that the protein Hsp104 must be present and active for prions to multiply and cause disease.
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06-02-2007 · EurekAlert!
Higher levels of a protein called S-100 in melanoma patients may correlate with a higher risk of the disease returning, say researchers at the University of Pittsburgh Cancer Institute. The study tested serum samples from 103 patients treated with high-dose interferon an average of eight years prior. When the researchers examined levels of S-100 in the samples, they found that the higher the level of the protein, the greater likelihood the disease had returned.
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