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Genes identified that protect against heart damage from chemotherapy

12-03-2007 · EurekAlert!

A series of genes that protect cells from the powerful, common chemotherapeutic agent doxorubicin has been identified by researchers working to understand how the drug also can destroy the heart.

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Keywords: genes, identified, protect, heart, damage, chemotherapy, gene

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  1. Gladstone scientists identify critical gene factor in heart development
    03-29-2007 · EurekAlert!
    Researchers at the Gladstone Institute of Cardiovascular Disease announced they have identified a critical genetic factor in the control of many aspects of heart form and function.
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  2. New gene test for prostate cancer at hand
    01-17-2008 · EurekAlert!
    Men with susceptibility for prostate cancer will soon be identifiable through a simple DNA test. So hope scientists at the Swedish medical university Karolinska Institutet, who have shown that men carrying a combination of known risk genes run a four to five times higher risk of developing prostate cancer. At present, men with suspected prostate cancer are identified mainly using what are known as PSA tests. However, the test has a relatively low sensitivity and better methods are needed.
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  3. Genes identified to protect brassicas from damaging disease
    11-01-2007 · EurekAlert!
    Scientists have identified a new way to breed brassicas, which include broccoli, cabbage and oilseed rape, resistant to a damaging virus. Their discovery has characterised a form of resistance that appears to be durable, broad-spectrum and unlikely to be overcome by the virus over time. Turnip mosaic virus is an economically devastating virus that infects a wide range of cultivated plants, but especially brassicas.
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  4. UNC scientists discover cellular 'SOS' signal in response to UV skin damage
    03-15-2007 · EurekAlert!
    New research from the University of North Carolina at Chapel Hill School of Medicine has identified two proteins that may help protect against skin cancer.
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  5. Study Identifies Possible Mechanism For Brain Damage In Huntington's Disease
    10-06-2006 · ScienceDaily
    Researchers from the MassGeneral Institute for Neurodegenerative Disease have identified a possible mechanism underlying how the gene mutation that causes Huntington's disease leads to the degeneration and death of brain cells.
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  6. Other highlights in the Nov. 13 JNCI
    11-13-2007 · EurekAlert!
    Other highlights in the Nov. 13 JNCI include a simple model to predict breast cancer risk, the link between smoking and rectal cancer, research into how a cancer drug causes heart damage, a gene that may inhibit lung cancer, BRCA1's influence on drug response, and the difficulties assigning patients to cancer subtypes.
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  7. Largest genomic search finds genes that may contribute to autism
    02-18-2007 · EurekAlert!
    An international team of researchers from 19 countries has identified one gene and previously unidentified region of another chromosome as the location of another gene that may contribute to a child's chances of having autism.
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  8. Research team identifies additional genetic risk factors for Crohn's disease
    04-15-2007 · EurekAlert!
    An international research team has identified several novel genetic variations associated with the risk of Crohn's disease. One of the identified genes establishes a role for autophagy, a previously unsuspected biological pathway, in Crohn's disease pathology, and the report documents functional studies which establish that this gene is integral to immune responses to intestinal bacteria.
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  9. High blood pressure in older adults traced to gene's effects in blood vessels
    01-10-2008 · EurekAlert!
    Scientists have identified the gene that sets off a sequence of events in the blood vessels of otherwise healthy adults that can lead to high blood pressure. The disease process eventually makes conditions in vessels ripe for the creation of blockages that can cause heart attacks, strokes and circulatory problems. The finding might lead to new therapeutic options for high blood pressure, especially hypertension associated with aging.
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  10. Scientists find genes involved in the battle between Hessian flies and wheat
    03-07-2007 · EurekAlert!
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