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Study: Re-engineered Gleevec reduces heart risks

Using a new bottom-up approach for rational drug design, researchers at Rice University and the University of Texas M. D. Anderson Cancer Center have reengineered the powerful anticancer drug imatinib -- best known by its brand name Gleevec -- to more specifically target one type of cancer while potentially curbing a rare life-threatening cardiotoxic side effect. The re-design strategy employed in the study is broadly applicable to reducing side effects in other drugs.

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Keywords: study, re-engineered, gleevec, heart, risks, engineered, risk

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