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New vaccine stimulates colorectal cancer patient's immune systems to fight cancerous cells
11-15-2006 · EurekAlert!British researchers have developed a vaccine that stimulates colorectal cancer patients' immune systems to fight cancerous cells.
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Keywords: vaccine, stimulates, colorectal, cancer, patient, immune, systems, fight, cancerous, cells, stimulate, system, cancerou, cell
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How cancer cells are killed could turn out to be an important element in activating a patient's immune system. A new study shows that one chemotherapy drug may kill tumor cells in such a way that the immune system can recognize the cancerous cells and help fight the disease more effectively.
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- Novel vaccine concept developed by scientists at the Wistar Institute
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A new vaccine design strategy developed by scientists at the Wistar Institute could help to develop vaccines against diseases like AIDS and cervical cancer. The secret is using a herpes simplex protein called glycoprotein D to block a receptor molecule on antigen-presenting cells. Wistar scientists showed that vaccine vectors made by fusing glycoprotein D with genes from HIV and HPV antigens increase the immune system's response to those antigens in cell cultures and mice.
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- Pancreatic cancer vaccine halts progression of disease in some patients
04-17-2007 · EurekAlert!
A dendritic cell-based therapeutic vaccine for pancreatic cancer developed by researchers at the University of Pittsburgh School of Medicine has successfully stalled the disease from progressing in a handful of patients three years post-vaccination. The results, part of a press briefing on cancer vaccines held at the annual meeting of the American Association of Cancer Research, provide promising evidence that the vaccine can trigger a patient's own immune system to rally against pancreatic cancer.
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- Cancer vaccines -- Taking a jab at cancer by stimulating the immune system
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- Promising treatment target found in Hodgkin lymphoma
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- Novel antigen-cloning technique may boost efforts to develop a melanoma vaccine
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Experimental vaccines to help the immune system fight tumors have rarely been designed to directly stimulate helper T cells, one of the body's most critical immune responders, because of the difficult process required to isolate and clone antigens for vaccine development. Now, a new technique may allow scientists to create a melanoma vaccine able to stimulate helper T cells. The approach may also aid in the development of other vaccines against cancers or infectious diseases.
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09-18-2007 · EurekAlert!
Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia, according to researchers at Memorial Sloan-Kettering Cancer Center. By administering repeated doses of T cells designed to express an artificial receptor which recognizes human B cells, the researchers were able to eradicate cancer in 44 percent of mice bearing human ALL tumors.
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- Patient with rare disorder responds to cancer drug
02-13-2008 · EurekAlert!
A rare disorder caused by an excess of two types of immune cells -- the mast cell found in various tissues and its blood-based twin, the basophil -- has successfully been treated with a cancer drug, report scientists from NIAID.
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- U of M researchers discover a pathway to turn off immune system cells
01-31-2008 · EurekAlert!
University of Minnesota researchers have discovered a new way to turn genes off in human T cells, a type of white blood cell that helps the immune system fight infections.Turning off genes, through a process known as mRNA decay, is important for regulating the body's immune response after fighting infection. This research could lead to development of new drugs that turn off the immune system in patients with autoimmune diseases -- such as rheumatoid arthritis and lupus.
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02-26-2007 · EurekAlert!
When cells begin to divide, they also activate a "braking system" that eventually stops cell division. When this system is faulty, uncontrolled cell division and the growth of cancer can result. Weizmann Institute scientists have identified a number of the genes involved in this braking system. Identification of the exact factors causing uncontrolled cell division may lead to the development of advanced treatments for cancer.
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