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Genetic switch for circadian rhythms discovered
12-12-2007 · EurekAlert!University of California, Irvine researchers have identified the chemical switch that triggers the genetic mechanism regulating our internal body clock.
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Keywords: genetic, switch, circadian, rhythms, discovered, rhythm
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- Oxford physiology professor earns APS' Walter B. Cannon Award
04-26-2007 · EurekAlert!
The American Physiological Society (APS) presents the Walter B. Cannon Award -- its highest award -- to Oxford University Physiology Professor Frances Ashcroft. Working with an Exeter colleague, she discovered a rare genetic form of diabetes that strikes children: permanent neonatal diabetes mellitus. This discovery produced dramatic changes in the lives of the children, including their ability to switch from daily insulin injections to a daily pill.
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- Daylight savings time disrupts humans' natural circadian rhythm
10-24-2007 · EurekAlert!
When people living in many parts of the world move their clocks forward one hour in the spring in observance of daylight savings time, their bodies' internal, daily rhythms don't adjust with them, reports a new study appearing online on Oct. 25 in Current Biology, a publication of Cell Press.
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- Study led by Scripps Research scientist reveals little-known cell networks vital to circadian rhythm
05-03-2007 · EurekAlert!
In a wide-ranging systems biology study of circadian rhythm, a multi-institutional collaboration led by Scripps Research Institute Professor Steve Kay has uncovered some little-known cellular mechanisms for sustaining circadian rhythm and limiting the impact of genetic clock mutations in mammals. The new findings could have important implications for future circadian studies, and point researchers toward new ways to manipulate human circadian rhythm at the molecular level to treat diseases such as bipolar disorder.
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- Clock gene plays role in weight gain, study finds
05-17-2007 · EurekAlert!
Scientists have discovered that a gene that participates in the regulation of the body's biological rhythms may also be a major control in regulating metabolism. Their finding shows that mice lacking the gene Nocturnin, which is regulated by the circadian clock in the organs and tissues of mammals, are resistant to weight gain when put on a high fat diet and also are resistant to the accumulation of fat in the liver.
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- Researchers find a common genetic risk factor for Parkinson's disease in Asians
01-16-2007 · EurekAlert!
Researchers at Mayo Clinic in Jacksonville, Fla. and the National Taiwan University Hospital in Taipei, Taiwan have discovered what to date appears to be the most common genetic risk factor for ParkinsonЎ's disease worldwide.
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- Why the switch stays on
12-12-2007 · EurekAlert!
North Carolina State University scientists have discovered the way in which a specific protein-protein interaction prevents the cell from turning one of its switches off, leading to uncontrolled cell proliferation -- one of the hallmarks of cancer.
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- UBC discovery unlocks tree genetics, gives new hope for pine beetle defense
01-14-2008 · EurekAlert!
UBC researchers have discovered some of the genetic secrets that enable pine and spruce trees to fight off pests and disease, uncovering critical new information about forests' natural defense systems.
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- Mouse model for schizophrenia has genetic on-off switch
09-10-2007 · EurekAlert!
The researchers developed the transgenic mouse by inserting the gene for mutant Disrupted-In-Schizophrenia-1 (DISC-1) into a normal mouse, along with a promoter that enables the gene to be switched on or off. Mutant DISC-1 was previously identified in a Scottish family with a strong history of schizophrenia and related mental disorders.
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- Mouse DNA to aid biomedical research
10-25-2006 · EurekAlert!
Researchers announced today that they have successfully resequenced the DNA of 15 mouse strains most commonly used in biomedical research. More than 8.3 million single nucleotide polymorphisms were discovered among the genomes of the 15 mouse strains and the data are now publicly available. These new data will help researchers better understand complex genetic traits, such as why some individuals are more susceptible to certain diseases, and will serve as a valuable resource in determining how environmental agents influence the development of disease.
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- Genetic archaeology offers clues to backstory of male pregnancy
12-04-2006 · EurekAlert!
A bit of genetic archaeology is giving clues to one of the greatest gender bending mysteries in the world of fish: How did a family of fish come to embrace male pregnancy?A new gene discovered in the gulf pipefish hints that an old gene busy with kidney and liver function may have learned new tricks in the male womb, said April Harlin-Cognato at Michigan State University in the Proceedings of the National Academy of Sciences.
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