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Penn researchers shine the light of venus to learn how the herpes virus invades cells
12-13-2007 · EurekAlert!University of Pennsylvania researchers have uncovered an important step in how herpes simplex virus, HSV-1, uses cooperating proteins found on its outer coat to gain entry into healthy cells and infect them. Further, the study’s authors say, they have demonstrated the effectiveness of monitoring these protein interactions using biomolecular complementation.
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Keywords: penn, researchers, shine, light, venus, learn, herpes, virus, invades, cells, researcher, venu, herpe, viru, invade, cell
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- An AIDS-related virus reveals more ways to cause cancer, Penn researchers find
10-08-2007 · EurekAlert!
Researchers have shed new light on how Kaposi's Sarcoma-associated Herpes Virus subverts normal cell machinery to cause cancer. A KSHV protein called latency-associated nuclear antigen (LANA) helps the virus hide out from the immune system in infected cells. When LANA takes the place of other proteins that control cell growth, it can cause uncontrolled cell replication.
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- An AIDS-related virus tricks cells to become tumors, new Penn study finds
11-08-2006 · EurekAlert!
Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi's sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth. The finding, published in the most recent issue of PLoS Pathogens, offers new potential strategies for treating Kaposi's sarcoma and other cancers associated with viruses
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- Penn Veterinary Medicine report new strategy to create genetically-modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Penn Veterinary Medicine report new strategy to create genetically modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Tissue Geometry Plays Crucial Role In Breast Cell Invasion
10-13-2006 · ScienceDaily
Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development. The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics, but also by geometry.
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- Clemson scientists shed light on molecules in living cells
08-21-2007 · EurekAlert!
Clemson University chemists have developed a method to dramatically improve the longevity of fluorescent nanoparticles that may someday help researchers track the motion of a single molecule as it travels through a living cell. The chemists are exploiting a process called "resonance energy transfer."
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- Researchers develop marker that identifies energy-producing centers in nerve cells
02-01-2007 · EurekAlert!
A protein that causes coral to glow is helping researchers at the University of Maryland School of Medicine to light up brain cells that are critical for the proper functioning of the central nervous system. This fluorescent marker protein may shed light on brain cell defects believed to play a role in various neurological diseases.
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- Tissue geometry plays crucial role in breast cell invasion
10-12-2006 · EurekAlert!
Researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory have created a first-of-its-kind model for studying how breast tissue is shaped and structured during development. The model may shed new light on how the misbehavior of only a few cells can facilitate metastatic invasion because it shows that the development of breast tissue, normal or abnormal, is controlled not only by genetics, but also by geometry.
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- Penn researchers discover new molecular path to fight autoimmune diseases
03-06-2007 · EurekAlert!
Multiple sclerosis, diabetes, and arthritis are among a variety of autoimmune diseases that are aggravated when one type of white blood cell, called the immune regulatory cell, malfunctions. In humans, one cause of this malfunction is when a mutation in a gene called FOXP3 disables the immune cells’ ability to function. Penn researchers have discovered how to modify enzymes that act on the FOXP3 protein, in turn making the regulatory immune cells work better.
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- Discredited Korean embryonic stem cells' true origins revealed
08-02-2007 · EurekAlert!
A report from researchers at Children's Hospital Boston and the Harvard Stem Cell Institute sheds new light on a now-discredited Korean embryonic stem cell line, setting the historical record straight and also establishing a much-needed set of standards for characterizing human embryonic stem cells. The report was published online Aug. 2 by the journal Cell Stem Cell.
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