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MicroRNA regulates cancer stem cells
12-13-2007 · EurekAlert!Researchers have discovered a key molecular switch that regulates cancer stem cells. This switch, which belongs to a class of molecules called microRNAs, can decrease a cancer stem cell's ability to propagate tumors. These findings offer a way for targeting cancer stem cells directly, and as a result open up new avenues for potentially treating cancer as a whole.
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Keywords: microrna, regulates, cancer, stem, cells, regulate, cell
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- Researchers first to map gene that regulates adult stem cell growth
01-14-2007 · EurekAlert!
A new discovery in stem cell research may mean big things for cancer patients in the future. After being the first to genetically map and identify a gene that regulates adult stem cells, the researchers investigated the gene's protein product, Latexin, which can be used to ramp up the body's stem cell count. The team's findings are being published in Nature Genetics.
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- Team finds way to create cancer stem cells
08-13-2007 · Massachusetts Institute of Technology (MIT)
MIT scientists and colleagues have found a way to create in the lab large amounts of cancer stem cells, or cells that can initiate tumors. The work, reported in the August 13 issue of Cancer Cell, could be a boon to researchers who study these elusive cells.
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- Study says normal but out-of-control enzyme may be culprit that signals some cells to become cancer
07-31-2007 · EurekAlert!
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- Cancer cells enlist adult stem cells to promote metastasis
10-31-2007 · Massachusetts Institute of Technology (MIT)
MIT and Whitehead institute scientists have managed to facilitate metastasis, finding evidence that some breast cancer cells recruit normal adult stem cells from bone marrow and force them to secrete a protein that fosters cancer cell movement and invasion.
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- Scientists find stem cell switch
07-26-2007 · EurekAlert!
Scientists have discovered how plant stem cells in roots detect soil structure and whether it is favourable for growth. Poor soil structure is a problem in tropical agriculture, where soil becomes compact as it dries out. Professor Liam Dolan, of the John Innes Centre in Norwich, UK and his team determined that the plant hormone ethylene regulates cell division in root stem cells.
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- New cell type identified in cancer development
03-13-2007 · EurekAlert!
A team of scientists, led by Dr. Jian-Xin Gao, a researcher in the department of pathology at Ohio State University Medical Center, has identified a new set of cells he calls precancerous stem cells (pCSCs).
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09-12-2007 · EurekAlert!
Scientists have identified a distinct subpopulation of cancer stem cells (CSCs) that is responsible for metastasis of a deadly human pancreatic cancer. The research, published by Cell Press in the Sept. issue of the journal Cell Stem Cell, provides insight into the role of CSCs in cancer initiation, progression and metastasis, and suggests new directions for development of more effective therapeutics.
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- OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
12-09-2007 · EurekAlert!
Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML). "We are looking under the surface of CML to understand better where the cancer is coming from. We have discovered abnormal cells in the early stem cell population in some CML patients, which don't belong to the CML clone. These are abnormal cells that are not part of the CML clone," said Thomas Bumm, M.D., OHSU Cancer Institute member.
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01-07-2008 · EurekAlert!
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- USC study in Nature Genetics supports a stem cell origin of cancer
01-08-2007 · EurekAlert!
Researchers at the University of Southern California found genes that are reversibly repressed in embryonic stem cells are over-represented among genes that are permanently silenced in cancers.
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