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WUSTL researchers spearhead key genome initiative
12-13-2007 · EurekAlert!The complete genome of a moss has been sequenced, providing scientists an important evolutionary link between single-celled algae and flowering plants, suggests a study published in the journal Science. A major landmark in understanding how plants originated, the moss genome sequencing offers insight into the conquest of land by plants and sheds light on the evolution of the plant kingdom, says study co-author Ralph S. Quatrano, a biology professor at Washington University in St. Louis.
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- International Team Analyzes Human Genetic Variation In Key Immune Region
09-30-2006 · ScienceDaily
An international group of researchers have unveiled a detailed map of human genetic variation within the major histocompatibility complex (MHC), the most important region of the human genome encoding the human response to infection, autoimmune disease and organ transplantation.
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- Lupus gene finding prompts call for more DNA samples
12-02-2007 · EurekAlert!
Wellcome Trust researchers have identified a key gene involved in the disease lupus, which affects around 50,000 people in the UK, mostly women. The lead researcher behind the study has called for more patients to volunteer DNA samples to enable them to further study the underlying causes of the disease.
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- Scientists map key landmarks in human genome
01-16-2007 · EurekAlert!
Dana-Farber Cancer Institute researchers have developed a powerful method for charting the positions of key gene-regulating molecules called nucleosomes throughout the human genome. The mapping tool could help uncover important clues for understanding and diagnosing cancer and other diseases, the scientists say. Moreover, it may shed light on the role of nucleosomes in the process of "reprogramming" an adult cell to its original embryonic state, which is a critical operation in cloning.
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- Neuron cell stickiness may hold key to evolution of the human brain
11-02-2006 · EurekAlert!
The stickiness of human neurons may have been a key factor in why the human brain evolved beyond the brains of our primate relatives. In a study comparing the genomes of humans, chimpanzees and other vertebrates, researchers at the US Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and Joint Genome Institute (JGI) found a strikingly high degree of genetic differences in DNA sequences that appear to regulate genes involved in nerve cell adhesion molecules.
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- As personal genomics stands poised to go mainstream, researchers urge caution
09-20-2007 · EurekAlert!
Imagine this: you visit your clinician, undergo genetic testing and then you are handed a miniature hard drive containing your personal genome sequence, which is subsequently uploaded onto publicly accessible databases. This may sound like science fiction, but it is scientific fact, and it is already happening. In an article published in the journal Science, University of Alberta researcher Tim Caulfield and co-authors highlight the need to proceed cautiously when it comes to personal genomics.
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- Genome sequencing reveals key to viable ethanol production
03-02-2007 · EurekAlert!
As the national push for alternative energy sources heats up, researchers at the University of Rochester have for the first time identified how genes responsible for biomass breakdown are turned on in a microorganism that produces valuable ethanol from materials like grass and cornstalks.Waste products such as grass clippings and wood chips -- once thought too difficult to turn into ethanol -- may soon be fodder for hungry, gene-tweaked bacteria.
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- HYMS researchers focus on human evolution
12-21-2006 · EurekAlert!
A Hull York Medical School researcher has played a key role in a study which has cast important new light on Neanderthals.
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- Genome-wide survey nets key melanoma gene
02-07-2008 · EurekAlert!
Howard Hughes Medical Institute researchers have uncovered a protein that stops the growth of melanoma, a cancer that develops from pigment-producing cells in the skin called melanocytes.
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- Genes key to high liver cancer rates in men
01-15-2008 · Massachusetts Institute of Technology (MIT)
A fundamental difference in the way males and females respond to chronic liver disease at the genetic level helps explain why men are more prone to liver cancer, according to MIT researchers, who conducted the first genome-wide study on the subject.
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- Gene Signatures Match Cancer And Other Diseases With Potentially Effective Drugs
09-29-2006 · ScienceDaily
In one of the most ambitious spinoffs of the human genome project, researchers at Dana-Farber Cancer Institute, Children's Hospital Boston, the Broad Institute of Harvard and MIT, and other collaborating centers have unveiled a new, systematic approach to drug discovery that matches diseases with potential treatments using a universal language based on cells' distinctive gene activity profiles, or "signatures."
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