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Scientists find mutations that let bird flu adapt to humans
11-15-2006 · EurekAlert!By comparing influenza viruses found in birds with those of the avian virus that have also infected human hosts, researchers have identified key genetic changes required for pandemic strains of bird flu.
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Keywords: scientists, mutations, let, bird, flu, adapt, humans, scientist, mutation, human
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- St. Jude influenza survey uncovers key differences between bird flu and human flu
08-20-2007 · EurekAlert!
Scientists at St. Jude Children's Research Hospital have found key features that distinguish influenza viruses found in birds from those that infect humans.
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- BCM, Rice scientists map flu's chemical key
10-15-2007 · EurekAlert!
Scientists from Baylor College of Medicine and Rice University have developed the first 3D, molecular map of the protein that allows influenza B to infect healthy cells with viral DNA. The research appears online this week in the Proceedings of the National Academy of Science. By studying influenza B, which affects only humans, researchers hope to shed light on the genetic mutations that would allow bird flu to spread among humans.
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- Latest IPCC report highlights need for integrated climate/human behavior models
04-06-2007 · EurekAlert!
How can humans adapt to climate change without adding even more stress to the environment? Scientists are now looking at ways to integrate the human dimension of climate change -- the choices we need to make to adapt to a changing global climate -- with the sophisticated climate prediction models used for the IPCC Assessment Reports. The goal: To evaluate the best ways forward.
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- 10 million people a year are affected by zoonotic viruses spread by non-human hosts
11-08-2006 · EurekAlert!
An estimated 50 million people were affected by zoonotics diseases, including H5N1 (bird flu), SARS and Rabies, between 2000 and 2005 and up to 78,000 died. No effective vaccines exist for the most common diseases. And the Dengue virus, which caused about a third of the deaths is experiencing a global resurgence. Zoonotic diseases can become serious killers if they adapt to human to human transmission -- HIV and Measles are two examples.
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- Updated WHO bird flu (H5N1) management guidance reinforces Tamiflu as first line treatment
08-22-2007 · EurekAlert!
The World Health Organization has reinforced that Tamiflu (oseltamivir) is the primary recommended antiviral of choice in managing patients infected with H5N1 in updated guidance published on the WHO website today. Experts believe that a human influenza pandemic is imminent and could be triggered by the highly pathogenic H5N1 strain, which, as of Aug. 16 2007, has infected 321 humans, causing 194 deaths worldwide.
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- Rhesus macaque genome may hold clues for human health and evolution
04-12-2007 · EurekAlert!
An international consortium of scientists has completed a draft sequence of the rhesus macaque genome, a species of non-human primate widely used for creating models of human diseases and infections. The study paves the way for researchers to watch disease progression at the genetic level in macaques, a close relative of humans. The findings, which appear April 13 in the journal Science, will let us learn how humans and other primates evolved into distinct species.
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- Drivers and passengers on the road to cancer
03-07-2007 · EurekAlert!
Scientists at the Wellcome Trust Sanger Institute have carried out the broadest survey yet of the human genome in cancer by sequencing more than 250 million letters of DNA code, covering more than 500 genes and 200 cancers. The survey shows that the number of mutated genes that drive development of cancer is greater than previously thought. Significantly, each cell type also carries many more passenger mutations that have hitchhiked along for the ride.
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- Scientists identify fundamental brain defect, probable drug target in fragile X syndrome
09-17-2007 · EurekAlert!
Scientists have discovered how the gene mutation responsible for fragile X syndrome -- the most common inherited form of mental retardation -- alters the way brain cells communicate. In neurons cultured from laboratory rats, the scientists also were able to reverse the effects of the mutation using a drug targeted to the specific site in an upstream pathway of the defect. The finding could lead to the development of human therapies for this previously untreatable condition.
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- Human embryonic stem cells derived from preimplantation genetically diagnosed embryos
11-14-2007 · EurekAlert!
A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
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- Researchers identify gene that plays key role in size of dogs
04-05-2007 · EurekAlert!
An international team of scientists, including researchers from Cornell University, have found a mutation in a single gene that plays a key role in determining body-size differences within and among dog breeds and probably is important in determining the size of humans as well.
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