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Mutant gene identified as villain in hardening of the arteries

A genetic mutation promotes hardening of the arteries.

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Keywords: mutant, gene, identified, villain, hardening, arteries, artery

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Similar news on "Mutant gene identified as villain in hardening of the arteries":

1. Link identified between age, cardiovascular disease
   11-02-2006 · EurekAlert!
   Researchers in the Linus Pauling Institute at Oregon State University have discovered a fundamental mechanism that causes aging blood vessels to lose their elasticity -- a literal "hardening of the arteries" that is often a prelude to high blood pressure and cardiovascular disease. An understanding of this mechanism provides an important new target for both drugs and dietary changes that might help prevent or treat atherosclerosis and heart disease.
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2. Mouse model for schizophrenia has genetic on-off switch
   09-10-2007 · EurekAlert!
   The researchers developed the transgenic mouse by inserting the gene for mutant Disrupted-In-Schizophrenia-1 (DISC-1) into a normal mouse, along with a promoter that enables the gene to be switched on or off. Mutant DISC-1 was previously identified in a Scottish family with a strong history of schizophrenia and related mental disorders.
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3. Air pollution link to clogged arteries
   07-25-2007 · EurekAlert!
   Should we be watching our exposure to airborne pollution as well as our cholesterol levels? Research now indicates that air pollution has a role to play in atherosclerosis (artery hardening), which can contribute to heart attacks or strokes. Findings published in the open access journal, Genome Biology, show how the fats that clog arteries work together with air pollution particles, triggering the genes behind inflammation.
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4. UCLA study links air pollution to clogged arteries
   07-25-2007 · EurekAlert!
   Got high cholesterol? Better stay away from air pollution. So says a new study linking diesel exhaust to atherosclerosis, or hardening of the arteries, which significantly increases one’s risk for heart attack and stroke. The research is the first to explain how fine particles in air pollution conspire with artery-clogging fats to switch on the genes that cause blood vessel inflammation and lead to cardiovascular disease.
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5. Mutant gene shatters nerves
   01-29-2007 · EurekAlert!
   If you bend a knee, the nerves stretch but do not break. A University of Utah study suggests why: A gene produces a springy protein that keeps nerve cells flexible. When the gene was disabled in tiny worms, their nerve cells literally broke. The discovery may provide a new explanation for a disease previously tied to a human version of the gene and identified in 11 generations of U.S. President Abraham Lincoln's family.
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6. Symptoms of depression linked to early stages of artery disease
   02-05-2007 · EurekAlert!
   Depressive symptoms -- especially physical signs, such as fatigue and loss of appetite -- may be associated with thickening arteries, which may reflect an early sign of coronary artery disease, according to a report in the February issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
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7. Treating obstructive sleep apnea, preventing heart attacks and strokes
   09-28-2007 · EurekAlert!
   Researchers in Brazil have found that treating patients who suffer from obstructive sleep apnea with continuous positive airway pressure dramatically reduces early indications of atherosclerosis in just months, linking OSA directly to the hardening or narrowing of the arteries. Until now, no study has demonstrated such a direct relationship between the two.
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8. Global positioning tracker may better gauge severity of peripheral artery disease
   02-04-2008 · EurekAlert!
   A space-based technology may provide an inexpensive and more reliable way to gauge the walking capacity in many patients with peripheral artery disease, whose clogged leg arteries cause them severe pain when they walk, according to a report in Circulation: Journal of the American Heart Association.
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9. Gene involved in common birth defect also regulates skin biology
   10-15-2006 · EurekAlert!
   Following up on an earlier discovery that a gene called IRF6 is involved in the common birth defect cleft lip and palate, University of Iowa researchers and their colleagues have identified the function of the gene. Their latest findings, published online Oct. 15 in Nature Genetics, reveal an unexpected role for IRF6 in the growth and development of skin cells, a discovery that may have implications for wound healing and cancer research.
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10. Circadian gene helps the brain predict mealtime
    10-23-2006 · EurekAlert!
    By investigating how animals can predict the timing of food availability, researchers have identified the first gene critical for anticipation of mealtime. This gene, called Period 2, is a key component of the circadian time-keeping system.
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