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Who is the arch-criminal in the development of hepatopulmonary syndrome?

12-19-2007 · EurekAlert!

Employing a rat model, Dr. Hui-ying Zhang et al. found that dynamic alterations of plasma endotoxin were closely associated with eNOS, iNOS, HO-1, number of capillaries and histological changes, and that exhibition of pulmonary vascular abnormalities is not only in vascular dilatation but in increased number, and that HO-1/CO and NOS/NO pathways may interrelate in pathogenesis of intra-pulmonary vascular abnormalities. All the above proved intestinal endotoxemia plays a leading role in the development of HPS.

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Keywords: arch-criminal, development, hepatopulmonary, syndrome, arch, criminal

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