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You can teach an old dog new tricks: anti-malarial prevents cancer in mice
12-20-2007 · EurekAlert!New data to be published in the Journal of Clinical Investigation, have indicated that the antimalarial drug chloroquine effectively prevents cancer in mouse models of two distinct human cancer syndromes, Burkitt lymphoma and ataxia telangiectasia.
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- JCI table of contents: Dec. 20, 2007
12-20-2007 · EurekAlert!
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published Dec. 20, 2007, in the JCI: "You can teach an old dog new tricks: antimalarial prevents cancer in mice"; "How an Atkins-like diet can treat epilepsy: Leptin attenuates rodent seizure severity"; "A new potential target in the treatment of a fatal brain disease"; "What AM I? AM is a regulator of vascular system functionality"; and others.
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- New behavior may use old genes
10-25-2006 · EurekAlert!
Though you may not be able to teach an old dog new tricks, ASU researchers have found that evolution may have taught old genes new tricks in the development of social behavior in honeybees. The genetic basis of social behavior is being deciphered through the efforts of ASU researchers and their work with the honeybee, Apis mellifera.
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- Cognitive lock-in: Why you can't teach an old dog new tricks
06-04-2007 · EurekAlert!
The ability to learn from experience is of central importance to human existence. It allows us to acquire the skills we need to complete complicated, multistep tasks in an efficient manner. It also creates habit -- a critical, if often overlooked factor in the choices consumers make. A new study from the Journal of Consumer Research demonstrates how this "cognitive lock-in" can cause us to remain loyal to a product, even if objectively better alternatives exist.
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- A fresh look at existing therapies: Researchers explore ways to teach approved drugs new tricks
10-24-2007 · EurekAlert!
Although all cancers are not alike, most share common causes, whether it is the result of a genetic mutation or faulty biochemical signaling pathway. For that reason, drugs developed specifically for one disease might have an impact on many others. Increasingly, researchers are discovering ways of combining new and existing drugs to fight cancer -- broadening the targets of already-approved targeted therapeutics.
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- Anti-cancer drug damages brain vessels
02-11-2008 · EurekAlert!
New research may help explain why an anti-cancer drug causes potentially fatal brain inflammation in certain patients. Scientists at Harvard Medical School mimicked the drug's activity in mice and found that it damaged the cell lining that prevents fluid from leaking from the spinal cord into the brain. The results will be published online on Feb. 11 in the Journal of Experimental Medicine.
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- Interfering with vagal nerve activity in mice prevents diabetes and hypertension
02-06-2007 · EurekAlert!
Interrupting nerve signals to the liver can prevent diabetes and hypertension in mice, according to scientists at Washington University School of Medicine in St. Louis. The finding is reported in the February issue of the journal Cell Metabolism. The research team surgically removed the vagus nerve in mice and found the procedure prevented or reversed the development of insulin resistance and high blood pressure in mice primed to develop these disorders through treatment with glucocorticoids.
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- Old viruses have new tricks
07-28-2007 · Science News Online
Invading viruses can trick a cell into turning off its defense mechanisms.
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- New vaccine prevents CMV infection and disease in mice
06-22-2007 · EurekAlert!
Researchers at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences have patented a strategy for developing a human vaccine to prevent against Human Cytomegalovirus (hCMV) infection and disease.
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- Peptide vaccine fights off breast tumors with aid of bacteria-mimicking agents
02-01-2007 · EurekAlert!
With the help of immune system-stimulating molecules that mimic bacterial components, researchers have used a type of cancer vaccine to both delay and prevent breast tumors in mice. The strategy, they say, holds promise for the future use of peptide vaccines in women who are at high risk for developing breast cancer.
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- Vaccine prevents prion disease in mice
05-03-2007 · EurekAlert!
An oral vaccine can prevent mice from developing a brain disease similar to mad cow disease, according to research that will be presented at the American Academy of Neurology's 59th annual Meeting in Boston, April 28-May 5, 2007. Prion diseases, which include scrapie, mad cow disease and chronic wasting disease, are fatal, and there is no treatment or cure.
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