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New strategies work to put cancer on the firing line
01-02-2008 · EurekAlert!Dr. Yukai He wants to put cancer in the bull's eye."Cancer really comes from us," the Medical College of Georgia Cancer Center immunologist says of the scary reality that cancer cells are our own cells gone awry. That means our immune system doesn't always see cancer as a horrific invader.
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- Prostate cancer: Watchful wait or vaccinate?
02-01-2008 · EurekAlert!
Researchers at the University of Southern California have developed a prostate cancer vaccine that prevented the development of cancer in 90 percent of young mice genetically predestined to develop the disease. In the Feb. 1 issue of Cancer Research, they suggest the same strategy might work for men with rising levels of PSA, a potential diagnostic indicator of prostate cancer
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- Unique role for blood formation gene identified
09-12-2007 · EurekAlert!
All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. Their research reveals an unexpected role for the gene in sustaining the adult blood-forming system, and opens novel strategies for targeting the gene, which is often involved in a type of childhood leukemia.
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- JCI table of contents: Dec. 13, 2007
12-13-2007 · EurekAlert!
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Dec. 13, 2007, in the JCI: Treatment with SN reduces injury to the brain following stroke; OutRAGEd by atherosclerosis; A Neu protein target in the treatment of breast cancers; The long and winding TRAIL to cancer; Stressed-out hearts put MEF2D to work; How an antibody makes the CD4+ T cell immune response more aggressive; and others.
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- Jefferson oncologists show breast cancers to be more aggressive in African-American women
07-09-2007 · EurekAlert!
A study of more than 2,200 women shows that African-Americans have more advanced breast cancer at the time of diagnosis than Caucasians. African-American women tend to have breast cancer tumor types that are more aggressive and have poorer prognoses. The findings are in line with other recent studies, and provide more evidence of the continuing need for early breast cancer screening for African-American women and the development of individual treatment strategies.
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- Koch grant puts nanotechnology on front line of prostate cancer battle
10-17-2007 · Massachusetts Institute of Technology (MIT)
A $5 million grant from David H. Koch (S.B. 1962, S.M. 1963) will help researchers from several institutions, including MIT, develop nanotechnology to treat metastatic prostate cancer, for which there is no effective treatment.
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- Novel vaccine concept developed by scientists at the Wistar Institute
01-31-2008 · EurekAlert!
A new vaccine design strategy developed by scientists at the Wistar Institute could help to develop vaccines against diseases like AIDS and cervical cancer. The secret is using a herpes simplex protein called glycoprotein D to block a receptor molecule on antigen-presenting cells. Wistar scientists showed that vaccine vectors made by fusing glycoprotein D with genes from HIV and HPV antigens increase the immune system's response to those antigens in cell cultures and mice.
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- On the defense: Conserved features of plant innate immunity
06-14-2007 · EurekAlert!
The innate immune response is the body's first line of defense against pathogen infection. In the June 15 issue of G&D, Dr. Xin Li (University of British Columbia) and colleagues report that three proteins work together in the MOS4-associated complex to execute innate immunity in the mustard weed, Arabidopsis.
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- The CReSA is working on a new strategy to combat spongiforms
10-31-2006 · EurekAlert!
Researchers at the Animal Health Research Centre (CReSA) are developing immunotherapeutical strategies against diseases produced by prion, such as Bovine Spongiform Encephalitis. The most recent results, published in the Journal of Virology, show that important advances have been made in tests using DNA vaccines on animal models, enabling a significant delay in the arrival of symptoms. In the long term, this research could lead to the production of treatment for humans.
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08-29-2007 · EurekAlert!
Psychologists have been assessing how well various study strategies produce long-term learning, and it appears that some strategies really do work much better than others.
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- Study offers innovative profile of enzyme that aids tumor growth
10-20-2006 · EurekAlert!
Using an innovative profiling strategy, scientists at the Scripps Research Institute have characterized an enzyme that is "highly elevated" in aggressive human tumor cells. When the enzyme, KIAA1363, was inactivated, it impaired tumor growth and migration in both ovarian and breast cancer cells, suggesting that inhibitors of this enzyme may prove valuable in the treatment of multiple types of cancer.
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